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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which 3 Foods to Avoid for Myelodysplastic Syndrome (MDS)?

Aug 11, 2021

Estimated reading time: 6 minutes
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Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Myelodysplastic Syndrome (MDS) needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Cucumber and Tomato should be eaten when undergoing Azacitidine treatment for Myelodysplastic Syndrome (MDS). On the same lines, avoid foods like Swiss Chard and Parsnip with treatment of Azacitidine for Myelodysplastic Syndrome (MDS). 

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Myelodysplastic Syndrome (MDS).



What is Myelodysplastic Syndrome (MDS)?

Myelodysplastic Syndrome (MDS) is a rare blood cancer that develops when the immature blood cells in the bone marrow do not mature or become healthy blood cells. The incidence rate of this cancer is only 4.5 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 71 years of age, however, it can occur in people of any age. It is more commonly found in men as compared to women.

Symptoms, diet, treatment for rare cancer - Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome (MDS) has prevalence of certain genetic changes. Some of the genes such as ASXL1, TET2, RUNX1, and TP53 are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Myelodysplastic Syndrome (MDS) can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Myelodysplastic Syndrome (MDS). Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Myelodysplastic Syndrome (MDS) genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Myelodysplastic Syndrome (MDS) nutrition may have to be redesigned.

Why Eating Right Matters for Myelodysplastic Syndrome (MDS)?

In Myelodysplastic Syndrome (MDS), activation or inhibition of some of the biochemical pathways including MYC Signaling, RAS-RAF Signaling, MRNA Splicing, NOTCH Signaling, Histone Methylation, Cancer Epigenetics, NFKB Signaling, Cell Cycle, JAK-STAT Signaling and PI3K-AKT-MTOR Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Myelodysplastic Syndrome (MDS), eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Azacitidine treatment for Myelodysplastic Syndrome (MDS)

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Myelodysplastic Syndrome (MDS) considering only one specific treatment – Azacitidine.

Foods to eat and avoid for Myelodysplastic Syndrome (MDS)

Foods to Avoid

Swiss Chard : Swiss Chard contains active ingredients such as Folic Acid, Retinol, Kaempferol and others. Folic Acid interferes with the impact of Azacitidine in Myelodysplastic Syndrome (MDS) by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Swiss Chard with Azacitidine treatment for Myelodysplastic Syndrome (MDS). 

Parsnip : Parsnip contains active ingredients such as Bergapten, Psoralen, Myristicin and others. Bergapten interferes with the impact of Azacitidine in Myelodysplastic Syndrome (MDS) by blocking a specific biological process called Histone Methylation. Hence, avoid foods like Parsnip with Azacitidine treatment for Myelodysplastic Syndrome (MDS). 

Foods to Eat

Cucumber : Cucumber contains active ingredients like Beta-sitosterol, Fisetin, Linolenic Acid. Intake of Beta-sitosterol along with Azacitidine treatment for Myelodysplastic Syndrome (MDS) causes a decrease in a specific biochemical pathway which is called Cancer Epigenetics, and this is a very positive effect. Cucumber hence should be eaten with Azacitidine treatment for Myelodysplastic Syndrome (MDS). (Nibedita Pradhan et al, Food Chem Toxicol., 2019; R Itzykson et al, Leukemia,. 2011)

Tomato : Tomato contains active ingredients like Glucaric Acid, Rutin, Quercitrin. Intake of Glucaric Acid along with Azacitidine treatment for Myelodysplastic Syndrome (MDS) causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Tomato hence should be eaten with Azacitidine treatment for Myelodysplastic Syndrome (MDS). (Prakash Tiwari et al, Biochimie., 2016; Claudio Festuccia et al, Endocr Relat Cancer., 2009; J Akutagawa et al, Leukemia., 2016)

Should I take this Nutritional Supplement for Myelodysplastic Syndrome (MDS)?

Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Azacitidine treatment. Black Seed supports the Azacitidine treatment for Myelodysplastic Syndrome (MDS) by decreasing the biochemical pathways/processes called MAPK Signaling, Cell Cycle, MYC Signaling, Notch Signaling and PI3K-AKT-MTOR Signaling and increasing pathways like Apoptosis. 

What are the Symptoms of Myelodysplastic Syndrome (MDS)?

In the initial stages, most cancers including Myelodysplastic Syndrome (MDS) may not cause any signs or symptoms. However, as the disease progresses, Myelodysplastic Syndrome (MDS) may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Myelodysplastic Syndrome (MDS).

  • Weakness and Fatigue
  • Breathlessness
  • Unusual paleness
  • Frequent infections
  • Easy bruising or bleeding
  • Nosebleeds
  • Red spots beneath the skin caused by bleeding

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Myelodysplastic Syndrome (MDS).

What are the Treatment Options for Myelodysplastic Syndrome (MDS)?

The treatment for Myelodysplastic Syndrome (MDS) may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, and whether the cancer was just diagnosed or had come back. The treatment options for Myelodysplastic Syndrome (MDS) include:

  • Blood transfusions
  • Bone marrow transplant
  • Chemotherapy
  • Immunosuppression treatment
  • Growth factors
  • Iron chelation (to control iron overload due to blood transfusions)

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Myelodysplastic Syndrome (MDS).

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Myelodysplastic Syndrome (MDS).

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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