No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Hodgkin Lymphoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Allspice and Almond should be eaten when undergoing Bleomycin treatment for Hodgkin Lymphoma. On the same lines, avoid foods like Brazil Nut and Chervil with treatment of Bleomycin for Hodgkin Lymphoma.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Hodgkin Lymphoma.
What is Hodgkin Lymphoma?
Hodgkin Lymphoma is a rare cancer that develops in the lymphatic system. It is a cancer that starts in white blood cells called lymphocytes. The incidence rate of this cancer is only 2.6 per 1 lakh people per year. This cancer is commonly diagnosed in young adults in their early 20s and older adults over the age of 70, however, it can occur in people of any age. It is slightly more commonly found in men as compared to women.
Hodgkin Lymphoma has prevalence of certain genetic changes. Some of the genes such as TP53, B2M, XPO1, and TNFAIP3 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Hodgkin Lymphoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Hodgkin Lymphoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Hodgkin Lymphoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Hodgkin Lymphoma nutrition may have to be redesigned.
Why Eating Right Matters for Hodgkin Lymphoma?
In Hodgkin Lymphoma, activation or inhibition of some of the biochemical pathways including P53 Signaling, Cell Cycle Checkpoints, JAK-STAT Signaling, DNA Repair and MYC Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Hodgkin Lymphoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Bleomycin treatment for Hodgkin Lymphoma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Hodgkin Lymphoma considering only one specific treatment- Bleomycin.
Foods to Avoid
Brazil Nut : Brazil Nut contains active ingredients such as Folic Acid, Vitamin E, Oleic Acid and others. Folic Acid interferes with the impact of Bleomycin in Hodgkin Lymphoma by activating a specific biochemical pathway called MYC Signaling. Hence, avoid foods like Brazil Nut with Bleomycin treatment for Hodgkin Lymphoma.
Chervil : Chervil contains active ingredients such as Folic Acid, Vitamin C, Linolenic Acid and others. Folic Acid interferes with the impact of Bleomycin in Hodgkin Lymphoma by activating a specific biochemical pathway called MYC Signaling. Hence, avoid foods like Chervil with Bleomycin treatment for Hodgkin Lymphoma.
Foods to Eat
Allspice : Allspice contains active ingredients like Eucalyptol, Salicylic Acid and Gallic Acid. Intake of Eucalyptol along with Bleomycin treatment for Hodgkin Lymphoma causes a decrease in a specific biochemical pathway which is called MYC Signaling, and this is a very positive effect. Allspice hence should be eaten with Bleomycin treatment for Hodgkin Lymphoma. (Dong Yeon Kim et al, Mol Nutr Food Res., 2018; Karen M Chisholmet al, Am J Surg Pathol., 2015)
Almond : Almond contains active ingredients like Geraniin, Salicylic Acid and Vitamin E. Intake of Geraniin along with Bleomycin treatment for Hodgkin Lymphoma causes a decrease in a specific biochemical pathway which is called JAK-STAT Signaling, and this is a very positive effect. Almond hence should be eaten with Bleomycin treatment for Hodgkin Lymphoma. (Zhong Ren et al, Cytotechnology., 2017, Enrico Tiacci et al, Blood., 2018)
Should I take this Nutritional Supplement for Hodgkin Lymphoma?
Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Bleomycin treatment. Black Seed supports the Bleomycin treatment for Hodgkin Lymphoma by decreasing the biochemical pathways such as JAK-STAT Signaling, MYC Signaling and DNA Repair.
What are the Symptoms of Hodgkin Lymphoma?
In the initial stages, most cancers including Hodgkin Lymphoma may not cause any signs or symptoms. However, as the disease progresses, Hodgkin Lymphoma may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Hodgkin Lymphoma.
- Persistent cough
- Frequent infections
- Night sweats
- Excessive bleeding
- Red spots under the skin
- Persistent itching all over the body
- Unintentional weight loss
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Hodgkin Lymphoma.
What are the Treatment Options for Hodgkin Lymphoma?
The treatment for Hodgkin Lymphoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, and whether the cancer was just diagnosed or had come back. The treatment options for Hodgkin Lymphoma include:
- Radiation therapy
- Bone marrow transplantation
- Targeted Therapy
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Hodgkin Lymphoma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Hodgkin Lymphoma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.