No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Ocular Melanoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Squash and Cabbage should be eaten when undergoing Radiation treatment for Ocular Melanoma. On the same lines, avoid foods like Yardlong Bean and Yam with treatment of Radiation for Ocular Melanoma.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Ocular Melanoma.
What is Ocular Melanoma?
Ocular Melanoma is a rare cancer that develops in the eye. The incidence rate of this cancer is only 5-6 per 1 lakh people per year in the United States. This cancer is commonly diagnosed in people who are about 70-80 years of age, however, it can occur in people of any age. It is more commonly found in Caucasians as compared to Africans.
Ocular Melanoma has prevalence of certain genetic changes. Some of the genes such as GNAQ, GNA11, SF3B1, and BAP1 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Ocular Melanoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Ocular Melanoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Ocular Melanoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Ocular Melanoma nutrition may have to be redesigned.
Why Eating Right Matters for Ocular Melanoma?
In Ocular Melanoma, activation or inhibition of some of the biochemical pathways including MAPK Signaling, MYC Signaling, Angiogenesis, TGFB Signaling, Platelet Aggregation, Focal Adhesion, Oxidative Stress, Cell Cycle, JAK-STAT Signaling, G-protein-coupled Receptor Signaling and PI3K-AKT-MTOR Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Ocular Melanoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Radiation treatment for Ocular Melanoma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Ocular Melanoma considering only one specific treatment- Radiation.
Foods to Avoid
Yardlong Bean : Yardlong Bean contains active ingredients such as Folic Acid, Linolenic Acid, Retinol and others. Folic Acid interferes with the impact of Radiation in Ocular Melanoma by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Yardlong Bean with Radiation treatment for Ocular Melanoma.
Yam : Yam contains active ingredients such as Citric Acid, Dioscin, Linolenic Acid and others. Citric Acid interferes with the impact of Radiation in Ocular Melanoma by blocking a specific biological process called Oxidative Stress. Hence, avoid foods like Yam with Radiation treatment for Ocular Melanoma.
Foods to Eat
Squash : Squash contains active ingredients like Beta-sitosterol, Linolenic Acid and, Retinol. Intake of Beta-sitosterol along with Radiation treatment for Ocular Melanoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Squash hence should be eaten with Radiation treatment for Ocular Melanoma. (Song Hyo Sook et al, Phytother Res., 2014; Michael A Davies, Cancer J., Mar-Apr 2012; Terje Sundstrøm et al, Acta Neuropathol Commun., 2019)
Cabbage : Cabbage contains active ingredients like Benzyl Isothiocyanate, Crocetin and Brassinin. Intake of Benzyl Isothiocyanate along with Radiation treatment for Ocular Melanoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Cabbage hence should be eaten with Radiation treatment for Ocular Melanoma. (Srinivas Reddy Boreddy et al, Clin Cancer Res., 2011; Kuang-Chi Lai et al, Int J Oncol., 2017)
Should I take this Nutritional Supplement for Ocular Melanoma?
Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Radiation treatment. Black Seed supports the Radiation treatment for Ocular Melanoma by decreasing the biochemical pathways/processes called Angiogenesis, MAPK Signaling, Focal Adhesion, JAK-STAT Signaling, MYC Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle, TGFB Signaling and increasing processes like Oxidative Stress.
What are the Symptoms of Ocular Melanoma?
In the initial stages, most cancers including Ocular Melanoma may not cause any signs or symptoms. However, as the disease progresses, Ocular Melanoma may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Ocular Melanoma.
- Change in the shape of the pupil
- Dark spot that keep keep getting bigger on the iris
- Reduced vision
- Fashes or floating dusts in your vision
- Loss of peripheral vision
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Ocular Melanoma.
What are the Treatment Options for Ocular Melanoma?
The treatment for Ocular Melanoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, and location and size of the cancer. The treatment options for Ocular Melanoma include:
- Radiation therapy
- Laser treatment
- Photodynamic therapy
Surgery is the most common treatment regimen for Ocular Melanoma.
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Ocular Melanoma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Ocular Melanoma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.