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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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For Which Cancer Types Should I Avoid Baicalin Supplement?

Aug 4, 2021

Estimated reading time: 8 minutes
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Highlights

Nutritional supplements like Baicalin have many health benefits and are being widely used by cancer patients and those at-genetic-risk of cancer. But, is it safe to take Baicalin supplements for all types of cancer and without considering any ongoing treatments and other lifestyle conditions? A common belief but only a myth is that anything natural can only benefit me or do no harm. As one example, the use of grapefruit with certain medications is not recommended. Another example, the use of spinach with some blood thinning medications can cause adverse interactions and should be avoided. For cancer, nutrition which includes the food and natural supplements has been shown to influence outcomes. Hence a frequently asked question by cancer patients to dieticians and doctors is “What Should I eat and What Should I Avoid?”. 

Taking nutritional Baicalin supplements can benefit Monoclonal Gammopathy of Undetermined Significance (MGUS) patients on Lenalidomide cancer treatment. But avoid Baicalin supplements if on Cytarabine treatment for Myeloproliferative Neoplasms. Similarly, taking nutritional supplement Baicalin can benefit healthy individuals who are at genetic risk of cancer due to mutation of gene CDKN1B. But avoid taking nutritional supplement Baicalin when at genetic risk of cancer due to mutation of gene TERT.

The takeaway being – your individual context will influence your decision if nutritional supplement Baicalin is safe or not. And also that this decision needs to be constantly revisited as conditions change. Conditions like cancer type, current ongoing treatments and supplements, age, gender, weight, height, lifestyle and any genetic mutations identified matter. So a legitimate question for you to ask for any recommendation of food and natural supplement is how it is related to your individual context.



Brief Overview

Nutritional supplements – vitamins, herbs, minerals, probiotics, and other specialty categories are increasing. Supplements  are high concentrations of active ingredients which are also found in different foods. The difference being foods contain more than one active ingredient at lower diffused concentrations. Remember that each of these ingredients has its own science and biological mechanism at molecular level – hence choose  the right combination of supplements like Baicalin based on individual context and conditions.

Baicalin Supplements for Cancer Treatment and Genetic Risk

 

So the question is should you take the supplement Baicalin? Should you take it when at genetic risk of cancer for mutation of gene TERT? Should you take it when at genetic risk of cancer for mutation of gene CDKN1B? Should you take it when diagnosed with Myeloproliferative Neoplasms? Should you take Baicalin supplements when diagnosed with Monoclonal Gammopathy of Undetermined Significance (MGUS)? Should you take it when on Cytarabine treatment? Should you continue taking Baicalin supplements if you change your treatment from Cytarabine to Lenalidomide? So a general explanation like – it is natural or it increases immunity may not be acceptable and sufficient for choosing Baicalin. 

Cancer

Cancer remains an unsolved problem statement. The improved availability of personalized treatments and monitoring of cancer via blood and saliva have been significant factors to improve outcomes. The earlier the intervention – the better the influence on outcome. Genetic testing has the potential to assess cancer risk and susceptibility early. But besides regular monitoring in most cases there are no therapeutic intervention options available. After diagnosis with cancer such as Myeloproliferative Neoplasms or Monoclonal Gammopathy of Undetermined Significance (MGUS), the treatments get personalized to tumor genomics and factors like staging of disease, age and gender. During cancer remission (after treatment cycle is complete) – monitoring is used for assessment of any relapse and accordingly decide next steps. A large majority of cancer patients and those at-risk do take nutritional supplements like Baicalin.

So the question is that are all genetic mutation risks and types of cancers to be considered as one when deciding the use of Baicalin? Are the biochemical pathway implications of genetic risk for cancer due to mutation of gene TERT the same as due to mutation of gene CDKN1B? Are the implications of taking Baicalin supplements in Myeloproliferative Neoplasms the same as Monoclonal Gammopathy of Undetermined Significance (MGUS)? Is it one and the same if you are on treatment with Cytarabine or on Lenalidomide? 

Baicalin – A Nutritional Supplement

Baicalin is a flavonoid found in certain medicinal herbs used in Traditional Chinese Medicine. It is also available in the form of dietary supplements. Following are some of the potential health benefits of Baicalin supplements: 

Medicinal plants such as Scutellaria baicalensis (Baikal skullcap or Chinese skullcap) and Scutellaria lateriflora (blue skullcap, mad dog skullcap, and side-flowering skullcap) contain Baicalin at different concentration levels along with other active ingredients. The molecular pathways which are regulated by Baicalin include Apoptosis, Stem Cell Signaling, Cell Cycle Checkpoints and FOXO Signaling. These cellular pathways directly or indirectly regulate specific cancer molecular endpoints like growth, spread and death. Because of this biological regulation – for cancer nutrition, the right choice of supplements like Baicalin individually or in combination is an important decision to be made. When making decisions on the use of supplement Baicalin for cancer – do consider all these factors and explanations. Because just as true for cancer treatments – Baicalin use cannot be a one-size-fits-all decision for all types of cancers.

Choosing Baicalin Supplements for Your Cancer

The reason there is no easy way to answer the question “When should I avoid Baicalin for Cancer” is because “It Depends!”. Just like the same treatment does not work for every cancer patient, based on your individual context the Baicalin may be harmful or safe. Along with which cancer and associated genetics – the ongoing treatments, supplements, lifestyle habits, BMI and allergies are all factors deciding if Baicalin should be avoided or not and why.

1. Will Baicalin Supplements benefit Cancer Patients with Myeloproliferative Neoplasms undergoing Cytarabine treatment?

Myeloproliferative Neoplasms is characterized and driven by specific genetic mutations like JAK2 and CALR. A cancer treatment like Cytarabine works through a specific pathway mechanism of action. The goal is to have a good overlap between the treatment and cancer driving pathways for a personalized approach which is effective. In such a condition any food or nutritional supplement which has a contrary effect to the treatment or reduces the overlap should be avoided. As an example, Baicalin should be avoided for Myeloproliferative Neoplasms along with treatment Cytarabine. Baicalin impacts specific pathways which either promote drivers of the disease and/or nullify the treatment effect. Some of the factors which should be considered when choosing nutrition are type of cancer, treatments and supplements being taken currently (if any), age, gender, BMI, lifestyle and any genetic mutation information (if available).

2. Will Baicalin Supplements benefit Monoclonal Gammopathy of Undetermined Significance (MGUS) Patients undergoing Lenalidomide Cancer Treatment?

Monoclonal Gammopathy of Undetermined Significance (MGUS) is characterized and driven by specific genetic mutations like LATS2 and ZMYM2. A cancer treatment like Lenalidomide works through specific pathway mechanisms. The goal is to have a good overlap between the treatment and cancer driving pathways for a personalized approach. In such a condition any food or nutritional supplement which has a compatible effect to the treatment or reduces the overlap should be considered. As an example, Baicalin supplements should be considered for Monoclonal Gammopathy of Undetermined Significance (MGUS) along with treatment Lenalidomide. Baicalin supplement impacts specific pathways which either obstruct drivers of MGUS and/or improve Lenalidomide treatment effect. 

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Are Baicalin Supplements Safe for Healthy Individuals with TERT Mutation Associated Genetic Risk?

Different companies offer panels of genes to be tested for assessing genetic risk to different cancers. These panels cover genes associated with cancers of the breast, ovary, uterus, prostate, and gastrointestinal system and others. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant may also guide testing and diagnosis of at-risk relatives. TERT is one of the genes generally available in panels for cancer risk testing. 

TERT mutation causes biochemical pathways/processes like Apoptosis, Cell Cycle Checkpoints, RUNX Signaling, Stem Cell Signaling and JAK-STAT Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Baicalin should be avoided when the genetic panel identifies mutation of TERT for Hematological Cancer. Baicalin impacts pathways/processes like Apoptosis and Cell Cycle Checkpoints and creates adverse effects with TERT and related conditions.

4. Are Baicalin Supplements Safe for Healthy Individuals with CDKN1B Mutation Associated Genetic Risk?

CDKN1B is one of the genes available in panels for cancer risk testing. CDKN1B mutation causes biochemical pathways/processes like Stem Cell Signaling, FOXO Signaling, Cell Cycle Checkpoints, PI3K-AKT-MTOR Signaling and Angiogenesis to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Consider taking Baicalin supplements when the genetic panel identifies mutation in CDKN1B for Neuroendocrine Cancer. Baicalin impacts pathways/processes like Stem Cell Signaling and FOXO Signaling and creates a supportive effect in those with CDKN1B mutation and related conditions. 

Which Cancer Types to Avoid Baicalin Supplement

* Other Factors are also included like BMI, Treatments, Lifestyle Habits

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition, which includes food and nutritional supplements like Baicalin, is an effective tool which can be controlled by you, while facing cancer.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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