Nutritional supplements like Pedra Hume Caa have many health benefits and are being widely used by cancer patients and those at-genetic-risk of cancer. But, is it safe to take Pedra Hume Caa supplements for all types of cancer and without considering any ongoing treatments and other lifestyle conditions? A common belief but only a myth is that anything natural can only benefit me or do no harm. As one example, the use of grapefruit with certain medications is not recommended. Another example, the use of spinach with some blood thinning medications can cause adverse interactions and should be avoided. For cancer, nutrition which includes the food and natural supplements has been shown to influence outcomes. Hence a frequently asked question by cancer patients to dieticians and doctors is “What Should I eat and What Should I Avoid?”.
Taking nutritional Pedra Hume Caa supplements can benefit cancer patients with Urachal Adenocarcinoma undergoing Fluorouracil treatment. But avoid Pedra Hume Caa supplements if on Ifosfamide treatment for Seminoma. Similarly, taking nutritional supplement Pedra Hume Caa can benefit healthy individuals who are at genetic risk of cancer due to mutation of gene RET. But avoid taking nutritional supplement Pedra Hume Caa when at genetic risk of cancer due to mutation of gene TERT.
The takeaway being – your individual context will influence your decision if nutritional supplement Pedra Hume Caa is safe or not. And also that this decision needs to be constantly revisited as conditions change. Conditions like cancer type, current ongoing treatments and supplements, age, gender, weight, height, lifestyle and any genetic mutations identified matter. So a legitimate question for you to ask for any recommendation of food and natural supplement is how it is related to your individual context.
Nutritional supplements – vitamins, herbs, minerals, probiotics, and other specialty categories are increasing. Supplements are high concentrations of active ingredients which are also found in different foods. The difference being foods contain more than one active ingredient at lower diffused concentrations. Remember that each of these ingredients has its own science and biological mechanism at molecular level – hence choose the right combination of supplements like Pedra Hume Caa based on individual context and conditions.
So the question is should you take the supplement Pedra Hume Caa? Should you take it when at genetic risk of cancer for mutation of gene TERT? Should you take it when at genetic risk of cancer for mutation of gene RET? Should you take it when diagnosed with Seminoma? Should you take Pedra Hume Caa supplement when diagnosed with Urachal Adenocarcinoma? Should you take it when on Ifosfamide treatment? Should you continue taking it if you change your treatment from Ifosfamide to Fluorouracil? So a general explanation like – it is natural or it increases immunity may not be acceptable and sufficient for choosing Pedra Hume Caa.
Cancer remains an unsolved problem statement. The improved availability of personalized treatments and monitoring of cancer via blood and saliva have been significant factors to improve outcomes. The earlier the intervention – the better the influence on outcome. Genetic testing has the potential to assess cancer risk and susceptibility early. But besides regular monitoring in most cases there are no therapeutic intervention options available. After diagnosis with cancer such as Seminoma or Urachal Adenocarcinoma, the treatments get personalized to tumor genomics and factors like staging of disease, age and gender. During cancer remission (after treatment cycle is complete) – monitoring is used for assessment of any relapse and accordingly decide next steps. A large majority of cancer patients and those at-risk do take nutritional supplements like Pedra Hume Caa.
So the question is that are all genetic mutation risks and types of cancers to be considered as one when deciding the use of Pedra Hume Caa? Are the biochemical pathway implications of genetic risk for cancer due to mutation of gene TERT the same as due to mutation of gene RET? Are the implications of Seminoma same as Urachal Adenocarcinoma? Is it one and the same if you are on treatment with Ifosfamide or on Fluorouracil?
Pedra Hume Caa – A Nutritional Supplement
Pedra hume caa or Myrcia salicifolia is a shrub with small, green leaves, commonly found in the Amazon regions and certain other parts of Brazil. The fruits of this plant are also known to have strong antioxidant and antiglycant properties. Pedra hume caa has been traditionally used as a natural antidiabetic food source and is also known as “vegetable insulin” or “insulina vegetal”. (Andrezza S Ramos et al, Food Research International, 2019)
Pedra hume caa is also considered to have anti-inflammatory and antimicrobial activities. (Márcia Moraes Cascaes et al, Int J Mol Sci., 2015) Pedra hume caa leaf extracts are also used for various other health conditions such as :
- High Blood Pressure
- Mouth Ulcers
Pedra Hume Caa is also commercially available in the form of dietary supplements.
Pedra Hume Caa supplements contain many active ingredients including Myrcene at different concentration levels. The molecular pathways which are regulated by Pedra Hume Caa include Oxidative Stress, Epithelial to Mesenchymal Transition, MYC Signaling, PI3K-AKT-MTOR Signaling and TGFB Signaling. These cellular pathways directly or indirectly regulate specific cancer molecular endpoints like growth, spread and death. Because of this biological regulation – for cancer nutrition, the right choice of supplements like Pedra Hume Caa individually or in combination is an important decision to be made. When making decisions on the use of supplement Pedra Hume Caa for cancer – do consider all these factors and explanations. Because just as true for cancer treatments – Pedra Hume Caa use cannot be a one-size-fits-all decision for all types of cancers.
Choosing Pedra Hume Caa Supplements for Your Cancer
The reason there is no easy way to answer the question “When should I avoid Pedra Hume Caa for Cancer” is because “It Depends!”. Just like the same treatment does not work for every cancer patient, based on your individual context the Pedra Hume Caa may be harmful or safe. Along with which cancer and associated genetics – the ongoing treatments, supplements, lifestyle habits, BMI and allergies are all factors deciding if Pedra Hume Caa should be avoided or not and why.
1. Will Pedra Hume Caa Supplements benefit Cancer Patients with Seminoma undergoing Ifosfamide treatment?
Seminoma is characterized and driven by specific genetic mutations like KIT and KRAS leading to biochemical pathway changes in Oxidative Stress, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling and MAPK Signaling. A cancer treatment like Ifosfamide works through a specific pathway mechanism of action. The goal is to have a good overlap between the treatment and cancer driving pathways for a personalized approach which is effective. In such a condition any food or nutritional supplement which has a contrary effect to the treatment or reduces the overlap should be avoided. As an example, Pedra Hume Caa should be avoided for Seminoma along with the treatment Ifosfamide. Pedra Hume Caa impacts pathways/processes like Oxidative Stress which either promote drivers of the disease and/or nullify the treatment effect. Additionally, Pedra Hume Caa supplements contain active ingredients like Myrcene which has CYP3A4 interactions with Ifosfamide treatment, and hence should be avoided by patients undergoing this treatment (Pius S. Fasinu et al, Front Oncol., 2019; Oliver Yoa-Pu Hu et al, Patent, 2002) Some of the factors which should be considered when choosing nutrition are type of cancer, treatments and supplements being taken currently (if any), age, gender, BMI, lifestyle and any genetic mutation information (if available).
2. Will Pedra Hume Caa Supplements benefit Cancer Patients with Urachal Adenocarcinoma undergoing Fluorouracil Treatment?
Urachal Adenocarcinoma is characterized and driven by specific genetic mutations like TP53 and MTOR leading to biochemical pathway changes in Epithelial to Mesenchymal Transition, MYC Signaling, PI3K-AKT-MTOR Signaling, Angiogenesis and MAPK Signaling. A cancer treatment like Fluorouracil works through specific pathway mechanisms. The goal is to have a good overlap between the treatment and cancer driving pathways for a personalized approach. In such a condition any food or nutritional supplement which has a compatible effect to the treatment or reduces the overlap should be considered. As an example, Pedra Hume Caa supplement should be considered for Urachal Adenocarcinoma along with treatment Fluorouracil. Pedra Hume Caa supplement impacts pathways/processes like Epithelial to Mesenchymal Transition and MYC Signaling which either obstruct drivers of Urachal Adenocarcinoma and/or improve the treatment effect.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
3. Are Pedra Hume Caa Supplements Safe for Healthy Individuals with TERT Mutation Associated Genetic Risk?
Different companies offer panels of genes to be tested for assessing genetic risk to different cancers. These panels cover genes associated with cancers of the breast, ovary, uterus, prostate, and gastrointestinal system and others. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant may also guide testing and diagnosis of at-risk relatives. TERT is one of the genes generally available in panels for cancer risk testing.
TERT mutation causes biochemical pathways/processes like MYC Signaling, TGFB Signaling, Nucleotide metabolism, Stem Cell Signaling and Hypoxia to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Pedra Hume Caa should be avoided when the genetic panel identifies mutation of TERT for Hematological Cancer. Pedra Hume Caa impacts pathways/processes like MYC Signaling and TGFB Signaling and creates adverse effects with TERT and related conditions.
4. Are Pedra Hume Caa Supplements Safe for Healthy Individuals with RET Mutation Associated Genetic Risk?
RET is one of the genes available in panels for cancer risk testing. RET mutation causes biochemical pathways/processes like PI3K-AKT-MTOR Signaling, MAPK Signaling, Stem Cell Signaling, Angiogenesis and Growth Factor Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Consider taking Pedra Hume Caa supplements when the genetic panel identifies mutation in RET for Thyroid Cancer and Neuroendocrine Cancer. Pedra Hume Caa impacts pathways/processes like PI3K-AKT-MTOR Signaling and MAPK Signaling and creates an additive effect with RET and related conditions.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition, which includes food and nutritional supplements like Pedra Hume Caa, is an effective tool which can be controlled by you, while facing cancer.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.