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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which 3 Foods to Avoid for Stomach Signet Ring Cell Carcinoma?

Apr 22, 2021

Estimated reading time: 10 minutes
Home » Blogs » Which 3 Foods to Avoid for Stomach Signet Ring Cell Carcinoma?

Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Stomach Signet Ring Cell Carcinoma (Stomach SRCC) needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Beetroot and Bell Pepper should be eaten when undergoing Docetaxel treatment for Stomach Signet Ring Cell Carcinoma. On the other hand, for Stomach Signet Ring Cell Carcinoma (Stomach SRCC), Basil and Cucumber should be eaten with treatment of Doxorubicin. On the same lines, avoid foods like Buttermilk and Cherry with treatment of Docetaxel for Stomach SRCC. If the treatment is Doxorubicin, then avoid Corn and Peppermint.

Black Seed contains an active ingredient called Thymoquinone. Thymoquinone has CYP (drug metabolizing enzyme) interactions with Docetaxel and Doxorubicin treatments and hence should be avoided.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Stomach Signet Ring Cell Carcinoma.



What is Stomach Signet Ring Cell Carcinoma?

Stomach Signet Ring Cell Carcinoma (Stomach SRCC) is a rare cancer that develops from the glandular cells in the stomach. The incidence rate of this cancer is only 1.273 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 63 years of age, however, it can occur in people of any age. It is more commonly found in Caucasians as compared to Asians/Pacific Islanders and African Americans.

Gastric/Stomach Signet Ring Cell Carcinoma - SRCC - Symptoms, Treatment, Diet, Foods

Stomach SRCC has prevalence of certain genetic changes. Some of the genes such as CDH1, TP53, ARID1A, and TGFBR2 are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Stomach Signet Ring Cell Carcinoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Stomach Signet Ring Cell Carcinoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Stomach SRCC, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Stomach Signet Ring Cell Carcinoma (Stomach SRCC) may have to be redesigned.

Why Eating Right Matters for Stomach Signet Ring Cell Carcinoma?

In Stomach Signet Ring Cell Carcinoma, activation or inhibition of some of the biochemical pathways including Apoptosis, Hypoxia, MAPK Signaling, P53 Signaling, Cell Cycle Checkpoints, Nutrient Sensing, MYC Signaling, Wnt Beta-catenin Signaling, Cancer Epigenetics, Epithelial To Mesenchymal Transition and PI3K-AKT-MTOR Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Stomach SRCC, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Docetaxel treatment for Stomach SRCC

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Stomach SRCC considering only the treatment changes.

Foods to Avoid

Buttermilk : Buttermilk contains active ingredients such as Lauric Acid, Retinol, Vitamin D3 and others. Lauric Acid interferes with the impact of Docetaxel in Stomach SRCC by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Buttermilk with Docetaxel treatment for Stomach SRCC. (Joo Y Lee et al, J Biol Chem., 2003; Ronald P Mensink et al, m J Clin Nutr., 2003; D M Rocha et al, Atherosclerosis., 2016; Yingying Meng et al, J Agric Food Chem., 2017; Rosamaria Lappano et al, Cell Death Discov., 2017; Simon Pernot et al, World J Gastroenterol., 2015; Yota Yasumizu et al, J Urol., 2014; Jeffrey J Wallin et al, Clin Cancer Res., 2012; Simon Pernot et al, Br J Cancer., 2018)

Cherry : Cherry contains active ingredients such as Chrysin, Oleic Acid, Isorhamnetin and others. Chrysin interferes with the impact of Docetaxel in Stomach SRCC by activating a specific biological process called Epithelial to Mesenchymal Transition. Hence, do not eat Cherry with Docetaxel treatment for Stomach SRCC. (Jinbao Guo et al, Med Oncol., 2015; Heshu Lu et al, J Med Chem., 2005; Cheng Zhang et al, Int J Ophthalmol., 2018; Vignesh Ramesh et al, Trends Cancer., 2020; Martin Puhr et al, Am J Pathol., 2012; Simon Pernot et al, Br J Cancer., 2018)

Foods to Eat

Beetroot :  Beetroot contains active ingredients like Vitamin E, Folic Acid and Oleic Acid. Intake of Vitamin E along with Docetaxel treatment for Stomach SRCC causes a decrease in a specific biochemical pathway which is called  PI3K-AKT-MTOR Signaling, and this is a very positive effect. Beetroot hence should be eaten with Docetaxel treatment for Stomach Signet Ring Cell Carcinoma. (Kwang Seok Ahn et al, J Biol Chem., 2007; Simon Pernot et al, World J Gastroenterol., 2015; Yota Yasumizu et al, J Urol., 2014; Jeffrey J Wallin et al, Clin Cancer Res., 2012; Simon Pernot et al, Br J Cancer., 2018)

Bell Pepper :  Bell Pepper contains active ingredients like Vitamin E, Folic Acid and Isorhamnetin. Intake of Vitamin E along with Docetaxel treatment for Stomach SRCC causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Bell Pepper hence should be eaten with Docetaxel treatment for Stomach Signet Ring Cell Carcinoma. (Kwang Seok Ahn et al, J Biol Chem., 2007; Simon Pernot et al, World J Gastroenterol., 2015; Yota Yasumizu et al, J Urol., 2014; Jeffrey J Wallin et al, Clin Cancer Res., 2012; Simon Pernot et al, Br J Cancer., 2018)

Should I take this Nutritional Supplement for Stomach Signet Ring Cell Carcinoma?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 interactions with Docetaxel treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Docetaxel treatment efficacy in Stomach Signet Ring Cell Carcinoma. Hence, avoid Black seed supplements with Docetaxel treatment for this cancer. (Ahmed A Albassam et al, Saudi Pharm J., 2018; Pius S Fasinu et al, Front Onco., 2019)

Example Foods to “Not Eat” and Eat with Doxorubicin treatment for Stomach Signet Ring Cell Carcinoma

Foods to Avoid

Corn : Corn contains active ingredients such as Aescin, Oleic Acid, Chrysoeriol and others. Aescin interferes with the impact of Doxorubicin in Stomach Signet Ring Cell Carcinoma by blocking a specific biological process called Cell Cycle Checkpoints. Hence, avoid foods like Corn with Doxorubicin treatment for Stomach SRCC.

Peppermint : Peppermint contains active ingredients such as Apigenin, Eriodictyol, Eucalyptol and others. Apigenin interferes with the impact of Doxorubicin in Stomach Signet Ring Cell Carcinoma by activating a specific biological process called Epithelial to Mesenchymal Transition. Hence, do not eat Peppermint with Doxorubicin treatment for Stomach SRCC. (Jodee L Johnson et al, J Med Food., 2011; Jinbao Guo et al, Med Oncol., 2015; Cheng Zhang et al, Int J Ophthalmol., 2018; Rong-Fei Han et al, Asian Pac J Cancer Prev., 2014; Jiahui Xu et al, Journal of Experimental & Clinical Cancer Research, 2017; Julita Machlowska et al, Cancer Manag Res., 2019)

Foods to Eat

Basil :  Basil contains active ingredients like Betulinic Acid, P-coumaric Acid, Isoeugenol. Intake of Betulinic Acid along with Doxorubicin treatment for Stomach Signet Ring Cell Carcinoma causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Basil hence should be eaten with Doxorubicin treatment for Stomach. (Yun Chen et al, Cell Biochem Funct., 2020; Weiping Liu et al, Am J Transl Res., 2019; Yaowei Ai et al, Oncol Lett., 2018; Yao-Wei Ai et al, Zhonghua Zhong Liu Za Zhi., 2008; Julita Machlowska et al, Cancer Manag Res., 2019)

Cucumber :  Cucumber contains active ingredients like Lupeol, Oleic Acid and Linolenic Acid. Intake of Lupeol along with Doxorubicin treatment for Stomach Signet Ring Cell Carcinoma causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Cucumber hence should be eaten with Doxorubicin treatment for Stomach Signet Ring Cell Carcinoma. (Xiao-Ting Wu et al, Int Immunopharmacol., 2013; Yan Liu et al, Naunyn Schmiedebergs Arch Pharmacol., 2015; Mohammad Saleem et al, Oncogene., 2004; Yaowei Ai et al, Oncol Lett., 2018; Yao-Wei Ai et al, Zhonghua Zhong Liu Za Zhi., 2008; Julita Machlowska et al, Cancer Manag Res., 2019)

Foods to eat and avoid for Stomach Signet Ring Cell Carcinoma

Should I take this Nutritional Supplement for Stomach Signet Ring Cell Carcinoma?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 interactions with Doxorubicin treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Doxorubicin treatment efficacy in Stomach SRCC. Hence, avoid Black seed supplements with Doxorubicin treatment for this cancer. (Ahmed A Albassam et al, Saudi Pharm J., 2018; Pius S Fasinu et al, Front Onco., 2019)

Which Foods To Avoid for Stomach Signet Ring Cell Carcinoma?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

What are the Symptoms of Stomach SRCC?

In the initial stages, most cancers including Stomach SRCC may not cause any signs or symptoms. However, as the disease progresses, Stomach SRCC may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Stomach SRCC.

  • Weight loss
  • Early satiety
  • Abdominal pain
  • Nausea
  • Vomiting
  • Indigestion
  • Bone pain (in case of metastasis)

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Stomach SRCC.

What are the Treatment Options for Stomach SRCC?

The treatment for Stomach SRCC may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Stomach SRCC:

  • Surgery
  • Chemotherapy
  • Radiotherapy
  • Immunotherapy
  • Targeted Therapy

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Stomach SRCC.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Stomach Signet Ring Cell Carcinoma.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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