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What should I Eat?

is the most common question asked by cancer patients.
Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

is the most common question asked by cancer patients. Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

Get your personalized nutrition plan for cancer at 

Get your personalized nutrition plan for cancer at

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Which 3 Foods to Avoid for Primitive Neuro-ectodermal Tumors?

Apr 20, 2021

Home » Blogs » Which 3 Foods to Avoid for Primitive Neuro-ectodermal Tumors?

Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Primitive Neuro-ectodermal Tumors needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Beetroot and Bell Pepper should be eaten when undergoing Temozolomide treatment for Primitive Neuro-ectodermal Tumors. On the other hand, for Primitive Neuro-ectodermal Tumors, Allspice and Almond should be eaten with treatment of Radiation. On the same lines, avoid foods like Buttermilk and Lard with treatment of Temozolomide for Primitive Neuro-ectodermal Tumors. If the treatment is Radiation, then avoid Common Bean.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Primitive Neuro-ectodermal Tumors.



What are Primitive Neuro-ectodermal Tumors?

Primitive Neuro-ectodermal Tumors are rare, central nervous system tumors that develop in the brain or spinal cord and belong to the Ewing family of tumors. These were thought to arise from primitive nerve cells. The incidence rate of this cancer is only 0.2–0.4 per 1 lakh people per year. This cancer is commonly diagnosed in children and young adults under 25 years of age, however, it can occur in people of any age. It is slightly more commonly found in men as compared to women.

Primitive Neuro-ectodermal Tumors - Symptoms, Treatment, Diet, Foods

Primitive Neuroectodermal Tumors have prevalence of certain genetic changes. Some of the genes such as BCOR, TERT, TP53, and PALB2 are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Primitive Neuroectodermal Tumors can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Primitive Neuro-ectodermal Tumors. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Primitive Neuroectodermal Tumors genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for this cancer nutrition may have to be redesigned. 

Why Eating Right Matters for Primitive Neuro-ectodermal Tumors?

In Primitive Neuroectodermal Tumors, activation or inhibition of some of the biochemical pathways including Cell Cycle, MAPK Signaling, DNA Repair, RAS-RAF Signaling, C-type Lectin Receptor Signaling, MYC Signaling, Epithelial To Mesenchymal Transition, TGFB Signaling, PI3K-AKT-MTOR Signaling and JAK-STAT Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Primitive Neuro-ectodermal Tumors, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Temozolomide treatment for Primitive Neuro-ectodermal Tumors

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Primitive Neuro-ectodermal Tumors considering only the treatment changes.

Foods to Avoid

Buttermilk : Buttermilk contains active ingredients such as Lauric Acid, Retinol, Vitamin D3 and others. Lauric Acid interferes with the impact of Temozolomide in Primitive Neuroectodermal Tumors by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, hence avoid taking foods like Buttermilk with Temozolomide treatment for Primitive Neuro-ectodermal Tumors. (Rosamaria Lappano et al, Cell Death Discov., 2017; Simona Caporali et al, J Transl Med., 2012; Mahlon D Johnson et al, Appl Immunohistochem Mol Morphol., 2013)

Lard : Lard contains active ingredients such as Myristic Acid, Palmitic Acid and others. Myristic Acid interferes with the impact of Temozolomide in Primitive Neuroectodermal Tumors by activating a specific biochemical pathway called MAPK Signaling. Hence, avoid foods like Lard with Temozolomide treatment for Primitive Neuro-ectodermal Tumors. (Sungjin Kim et al, J Biol Chem., 2017; Atsushi Sato et al, Stem Cells., 2011; Mahlon D Johnson et al, Appl Immunohistochem Mol Morphol., 2013)

Foods to Eat

Beetroot :  Beetroot contains active ingredients like Vitamin E, Folic Acid and Oleic Acid. Intake of Vitamin E along with Temozolomide treatment for Primitive Neuroectodermal Tumors causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Beetroot hence should be eaten with Temozolomide treatment for this cancer. (Kwang Seok Ahn et al, J Biol Chem., 2007; Simona Caporali et al, J Transl Med., 2012; Mahlon D Johnson et al, Appl Immunohistochem Mol Morphol., 2013)

Bell Pepper :  Bell Pepper contains active ingredients like Vitamin E, Folic Acid and Isorhamnetin. Intake of Vitamin E along with Temozolomide treatment for Primitive Neuroectodermal Tumors causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Bell Pepper hence should be eaten with Temozolomide treatment for this cancer. (Amirah Abdul Rahman et al, BMC Complement Altern Med., 2014; Simona Caporali et al, J Transl Med., 2012; Mahlon D Johnson et al, Appl Immunohistochem Mol Morphol., 2013)

Should I take this Nutritional Supplement for Primitive Neuro-ectodermal Tumors?

Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Temozolomide treatment. Black Seed supports the Temozolomide treatment for Primitive Neuroectodermal Tumors by decreasing the biochemical pathways called MAPK Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling. (Mona Pazhouhi et al, Iran J Basic Med Sci., 2016; Fabliha Ahmed Chowdhury et al, Biomed Res Int., 2018)

Example Foods to “Not Eat” and Eat with Radiation treatment for Primitive Neuro-ectodermal Tumors

Foods to Avoid

Common Bean : Common Bean contains active ingredients such as Apigenin, Oleic Acid, Gamma-linolenic Acid and others. Apigenin interferes with the impact of Radiation in Primitive Neuroectodermal Tumors by activating a specific biological process called DNA Repair. Hence, do not eat Common Bean with Radiation treatment for Primitive Neuro-ectodermal Tumors. (Sreemanti Das et al, J Acupunct Meridian Stud., 2013; Haripaul Sharma et al, PLoS One., 2014; S Mary Britto et al, Mutat Res., 2017; D W Abbott et al, J Biol Chem., 1999; Seo Hee Choi et al, PLoS One., 2016)

Foods to Eat

Allspice :  Allspice contains active ingredients like Salicylic Acid, Vitamin C and Eugenol. Intake of Salicylic Acid along with Radiation treatment for Primitive Neuroectodermal Tumors causes a decrease  in a specific biological process which is called DNA Repair, and this is a very positive effect. Allspice hence should be eaten with Radiation treatment for Primitive Neuro-ectodermal Tumors. (H K Dibra et al, Oncol Rep., 2010; D W Abbott et al, J Biol Chem., 1999; Seo Hee Choi et al, PLoS One., 2016)

Almond :  Almond contains active ingredients like Salicylic Acid, Oleic Acid and Linolenic Acid. Intake of Salicylic Acid along with Radiation treatment for Primitive Neuroectodermal Tumors causes a decrease  in a specific biological process which is called DNA Repair, and this is a very positive effect. Almond hence should be eaten with Radiation treatment for Primitive Neuro-ectodermal Tumors. (H K Dibra et al, Oncol Rep., 2010; D W Abbott et al, J Biol Chem., 1999; Seo Hee Choi et al, PLoS One., 2016)

Should I take this Nutritional Supplement for Primitive Neuro-ectodermal Tumors?

Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Radiation treatment. Black Seed supports the Radiation treatment for Primitive Neuroectodermal Tumors by decreasing the biochemical pathways/processes like Epithelial to Mesenchymal Transition, MAPK Signaling, JAK-STAT Signaling, MYC Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle, DNA Repair, TGFB Signaling, C-type Lectin Receptor Signaling and RAS-RAF Signaling. (Reelma Velho-Pereira et al, Cell Biol Int., 2011)

Science of Right Personalized Nutrition for Cancer

Top 10 Foods and Supplements to Avoid for Cancer

Go beyond same nutrition guidelines for everyone and make personalized decisions with confidence.

What are the Symptoms of Primitive Neuro-ectodermal Tumors?

In the initial stages, most cancers including Primitive Neuro-ectodermal Tumors may not cause any signs or symptoms. However, as the disease progresses, Primitive Neuro-ectodermal Tumors may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Primitive Neuro-ectodermal Tumors.

  • Seizures
  • Headaches
  • Numbness
  • Fatigue/weakness
  • Memory problems
  • Problems with balance and movement
  • Bladder incontinence
  • Back pain
  • Leg pain

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Primitive Neuro-ectodermal Tumors.

What are the Treatment Options for Primitive Neuro-ectodermal Tumors?

The treatment for Primitive Neuroectodermal Tumors may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Primitive Neuro-ectodermal Tumors include:

  • Surgery
  • Radiation
  • Chemotherapy
  • Targeted Therapy
  • Immunotherapy

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Primitive Neuro-ectodermal Tumors.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Primitive Neuro-ectodermal Tumors.

“What should I eat?” is the most frequently asked question to cancer dieticians and physicians. The right answer depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan keeps you safe from adverse nutrition interactions.

Get started NOW with answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

Top 10 Foods and Supplements to Avoid for Cancer

Go beyond same nutrition guidelines for everyone and make personalized decisions with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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