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What should I Eat?

is the most common question asked by cancer patients.
Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

is the most common question asked by cancer patients. Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

Get your personalized nutrition plan for cancer at 

Get your personalized nutrition plan for cancer at

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Which 3 Foods to Avoid for Pancreatic Acinar Cell Carcinoma?

Apr 20, 2021

Home » Blogs » Which 3 Foods to Avoid for Pancreatic Acinar Cell Carcinoma?

Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Pancreatic Acinar Cell Carcinoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Buckwheat and Cabbage should be eaten when undergoing treatment for Pancreatic Acinar Cell Carcinoma. On the same lines, avoid foods like Lard and Tallow with treatment of Gemcitabine for Pancreatic Acinar Cell Carcinoma.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Pancreatic Acinar Cell Carcinoma.



What is Pancreatic Acinar Cell Carcinoma?

Pancreatic Acinar Cell Carcinoma is a rare cancer that constitutes 1-2 % of all pancreatic cancers. The incidence rate of this cancer is only 0.02-0.05 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 62 years of age, however, it can occur in people of any age. It is more commonly found in white males as compared to other ethnic groups.

Pancreatic Acinar Cell Carcinoma - Symptoms, treatment, diet, foods

Pancreatic Acinar Cell Carcinoma has prevalence of certain genetic changes. Some of the genes such as SMAD4, JAK1, LRP1, and TTN are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Pancreatic Acinar Cell Carcinoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Pancreatic Acinar Cell Carcinoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Pancreatic Acinar Cell Carcinoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Pancreatic Acinar Cell Carcinoma nutrition may have to be redesigned.

Why Eating Right Matters for Pancreatic Acinar Cell Carcinoma?

In Pancreatic Acinar Cell Carcinoma, activation or inhibition of some of the biochemical pathways including MAPK Signaling, Extracellular Matrix Remodelling, DNA Repair, Small Molecule Transport, Notch Signaling, Wnt Beta-catenin Signaling, Epithelial To Mesenchymal Transition and PI3K-AKT-MTOR Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Pancreatic Acinar Cell Carcinoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Gemcitabine treatment for Pancreatic Acinar Cell Carcinoma

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Pancreatic Acinar Cell Carcinoma considering only one specific treatment.

Foods to Avoid

Lard : Lard contains active ingredients such as Myristic Acid, Palmitic Acid and others. Myristic Acid interferes with the impact of Gemcitabine in Pancreatic Acinar Cell Carcinoma by activating a specific biological process called DNA Repair. Hence, do not eat Lard with Gemcitabine treatment for Pancreatic Acinar Cell Carcinoma. (Gail L Matters et al, Dig Dis Sci., 2014; Sandeep Nadella et al, Am J Physiol Gastrointest Liver Physiol., 2018; Hong-Quan Duong et al, J Cell Mol Med., 2013; Toru Furukawa et al, Sci Rep., 2015)

Tallow : Tallow contains active ingredients such as Lauric Acid, Myristic Acid, Palmitic Acid and others. Lauric Acid interferes with the impact of Gemcitabine in Pancreatic Acinar Cell Carcinoma by activating a specific biochemical pathway called MAPK Signaling. Hence, do not eat Tallow with Gemcitabine treatment for Pancreatic Acinar Cell Carcinoma. (Gail L Matters et al, Dig Dis Sci., 2014; Sandeep Nadella et al, Am J Physiol Gastrointest Liver Physiol., 2018; Zhi Xiao et al, Anat Rec (Hoboken)., 2012; Owen W J Prall et al, Mod Pathol., 2020)

Foods to Eat

Buckwheat :  Buckwheat contains active ingredients like Vitamin E, Folic Acid and Oleic Acid. Intake of Vitamin E along with Gemcitabine treatment for Pancreatic Acinar Cell Carcinoma causes a decrease  in a specific biological process which is called DNA Repair, and this is a very positive effect. Buckwheat hence should be eaten with Gemcitabine treatment for Pancreatic Acinar Cell Carcinoma. (Kazim Husain et al, Mol Cancer Ther., 2011; Ajaikumar B Kunnumakkara et al, Cancer Res., 2010; Hong-Quan Duong et al, J Cell Mol Med., 2013; Toru Furukawa et al, Sci Rep., 2015)

Cabbage :  Cabbage contains active ingredients like Benzyl Isothiocyanate, Isorhamnetin and Vitamin C. Intake of Benzyl Isothiocyanate along with Gemcitabine treatment for Pancreatic Acinar Cell Carcinoma causes a decrease  in a specific biological process which is called DNA Repair, and this is a very positive effect. Cabbage hence should be eaten with Gemcitabine treatment for Pancreatic Acinar Cell Carcinoma. (Srinivas Reddy Boreddy et al, Clin Cancer Res., 2011; Hong-Quan Duong et al, J Cell Mol Med., 2013; Toru Furukawa et al, Sci Rep., 2015)

Should I take this Nutritional Supplement for Pancreatic Acinar Cell Carcinoma?

Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Gemcitabine treatment. Black Seed supports the Gemcitabine treatment for Pancreatic Acinar Cell Carcinoma by decreasing the biochemical pathways/processes like Epithelial to Mesenchymal Transition, MAPK Signaling, Notch Signaling, PI3K-AKT-MTOR Signaling, DNA Repair, WNT Beta-catenin Signaling. (Sanjeev Banerjee et al, Cancer Res., 2009; Daniel Relles et al, Clin Cancer Res., 2011)

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What are the Symptoms of Pancreatic Acinar Cell Carcinoma?

In the initial stages, most cancers including Pancreatic Acinar Cell Carcinoma may not cause any signs or symptoms. However, as the disease progresses, Pancreatic Acinar Cell Carcinoma may start showing symptoms. 

Following are some of the signs and symptoms (mostly non-specific) that may be caused by Pancreatic Acinar Cell Carcinoma.

  • Abdominal pain
  • Nausea
  • Weight loss
  • Skin rashes
  • Joint pain
  • Increased number of eosinophils in blood

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Pancreatic Acinar Cell Carcinoma.

What are the Treatment Options for Pancreatic Acinar Cell Carcinoma?

The treatment for Pancreatic Acinar Cell Carcinoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Pancreatic Acinar Cell Carcinoma include:

  • Surgery
  • Chemotherapy
  • Radiation Therapy

Surgery is the most common treatment regimen for early stage Pancreatic Acinar Cell Carcinoma. Radiotherapy and chemotherapy are commonly used for the treatment of advanced/metastatic disease. As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Pancreatic Acinar Cell Carcinoma.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Pancreatic Acinar Cell Carcinoma.

“What should I eat?” is the most frequently asked question to cancer dieticians and physicians. The right answer depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan keeps you safe from adverse nutrition interactions.

Get started NOW with answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

Top 10 Foods and Supplements to Avoid for Cancer

Go beyond same nutrition guidelines for everyone and make personalized decisions with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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