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What Foods are Recommended for Cancer?
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.

Which Foods are Recommended for Choroid Plexus Carcinoma/Tumors?

Apr 17, 2021

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Highlights

No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Choroid Plexus Tumors when undergoing chemotherapy or when you determine you have a genetic risk for developing Choroid Plexus Tumors because of CIITA and POLQ gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.

There is no one answer to this question for cancers such as Choroid Plexus Tumors which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.

In short – the process to answer questions like “Should I Avoid eating fruit Cranberry” or “Include fruit Pomegranate in my diet” or “Should I reduce consumption of vegetable Spinach” or “Can I take Cordyceps and Psyllium supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.

RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO CHOROID PLEXUS TUMORS, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.

The overall objective of personalized nutrition for Choroid Plexus Tumors is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.

RECOMMENDATION: UPDATE YOUR NUTRITION FOR CHOROID PLEXUS TUMORS, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.



About Choroid Plexus Tumors

cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.

Following key highlights are derived from clinical data for Choroid Plexus Tumors from cBioPortal. The top genes with mutations and other abnormalities for Choroid Plexus Tumors include genes TERT, TP53, CIITA, POLQ and IDH1. The occurrence frequency distribution for these genes respectively is 25.0%, 22.2%, 12.5%, 11.8% and 11.1%. These tumor genetic details of Choroid Plexus Tumors are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Choroid Plexus Tumors.

Significance of Nutrition for Choroid Plexus Tumors

All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Choroid Plexus Tumors. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.

For example Cranberry includes active ingredients Vitamin C, Ellagic Acid, Quercetin, Resveratrol, Myricetin and others. And Pomegranate contains active ingredients Betulinic Acid, Epigallocatechin Gallate, Apigenin, Beta-sitosterol, Corilagin and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.

For cancers like Choroid Plexus Tumors, activation or inhibition of selected biochemical pathways like DNA Repair, Hypoxia, Apoptosis, MAPK Signaling plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Choroid Plexus Tumors, while eating some other foods and supplements may not be recommended.

One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

For cancers like Choroid Plexus Tumors, activation or inhibition of selected biochemical pathways like DNA Repair, Hypoxia, Apoptosis, MAPK Signaling plays an important role in driving cancer growth.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR CHOROID PLEXUS TUMORS – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.

Foods for Choroid Plexus Tumors undergoing chemotherapy treatment

In Choroid Plexus Tumors – the genes TERT, TP53, CIITA, POLQ and IDH1 have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Choroid Plexus Tumors are DNA Repair, Hypoxia, PI3K-AKT-MTOR Signaling and others. Etoposide is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers DNA Repair, Hypoxia, PI3K-AKT-MTOR Signaling so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.

RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.

Eat more pulses, Common Pea or Pigeon Pea?

Pulses are an important part of many diets. The active ingredients contained in Common Pea are Oleic Acid, Daidzein, Lupeol, Beta-sitosterol, Vitamin C among others. While the active ingredients contained in Pigeon Pea are Oleic Acid, Vitamin C, Linolenic Acid, Genistein, Vitamin A and others.

Beta-sitosterol can manipulate biochemical pathways MYC Signaling, WNT Beta Catenin Signaling and Hypoxia. Vitamin C has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MYC Signaling and WNT Beta Catenin Signaling.

Genistein can manipulate biochemical pathways DNA Repair. Folic Acid has biological action on biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. And so on.

When treating Choroid Plexus Tumors with chemotherapy Etoposide – Foods like Common Pea are recommended compared to Pigeon Pea. This is because the active ingredients Genistein and Folic Acid in Pigeon Pea interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Beta-sitosterol and Vitamin C contained in Common Pea support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: COMMON PEA IS RECOMMENDED OVER PIGEON PEA FOR CHOROID PLEXUS TUMORS ON TREATMENT WITH CHEMOTHERAPY ETOPOSIDE FOR SOME CONDITIONS.

Eat more vegetables, Potato or Spinach?

Vegetables are an important part of many diets. The active ingredients contained in Potato are Oleic Acid, Beta-sitosterol, Vitamin C, Gallic Acid, Linolenic Acid among others. While the active ingredients contained in Spinach are Oleic Acid, Apigenin, Beta-sitosterol, Vitamin C, Quercetin and others.

Beta-sitosterol can manipulate biochemical pathways MYC Signaling, WNT Beta Catenin Signaling and Hypoxia. Vitamin C has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MYC Signaling and WNT Beta Catenin Signaling.

Apigenin can manipulate biochemical pathways DNA Repair. Folic Acid has biological action on biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. And so on.

When treating Choroid Plexus Tumors with chemotherapy Etoposide – Foods like Potato are recommended compared to Spinach. This is because the active ingredients Apigenin and Folic Acid in Spinach interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Beta-sitosterol and Vitamin C contained in Potato support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: POTATO IS RECOMMENDED OVER SPINACH FOR CHOROID PLEXUS TUMORS ON TREATMENT WITH CHEMOTHERAPY ETOPOSIDE FOR SOME CONDITIONS.

Which Foods are Recommended for Choroid Plexus Tumors?

Eat more fruits, Pomegranate or Cranberry?

Fruits are an important part of many diets. The active ingredients contained in Pomegranate are Betulinic Acid, Epigallocatechin Gallate, Apigenin, Beta-sitosterol, Corilagin among others. While the active ingredients contained in Cranberry are Vitamin C, Ellagic Acid, Quercetin, Resveratrol, Myricetin and others.

Betulinic Acid can manipulate biochemical pathways MYC Signaling, WNT Beta Catenin Signaling and Hedgehog Signaling. Gallic Acid has biological action on biochemical pathways DNA Repair, Hypoxia and PI3K-AKT-MTOR Signaling.

Ellagic Acid can manipulate biochemical pathways MYC Signaling and WNT Beta Catenin Signaling. Resveratrol has biological action on biochemical pathways DNA Repair. And so on.

When treating Choroid Plexus Tumors with chemotherapy Etoposide – Foods like Pomegranate are recommended compared to Cranberry. This is because the active ingredients Ellagic Acid and Resveratrol in Cranberry interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Betulinic Acid and Gallic Acid contained in Pomegranate support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: POMEGRANATE IS RECOMMENDED OVER CRANBERRY FOR CHOROID PLEXUS TUMORS ON TREATMENT WITH CHEMOTHERAPY ETOPOSIDE FOR SOME CONDITIONS.

Eat more nuts, Pecan Nut or Chestnut?

Nuts are an important part of many diets. The active ingredients contained in Pecan Nut are Oleic Acid, Vitamin E, Linolenic Acid, Cianidanol, Vitamin A among others. While the active ingredients contained in Chestnut are Oleic Acid, Vitamin C, Ellagic Acid, Quercetin, Gallic Acid and others.

Vitamin E can manipulate biochemical pathways MYC Signaling, DNA Repair and Hypoxia. Cianidanol has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MYC Signaling and Hypoxia.

Ellagic Acid can manipulate biochemical pathways MYC Signaling and WNT Beta Catenin Signaling. Folic Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling and MYC Signaling. And so on.

When treating Choroid Plexus Tumors with chemotherapy Etoposide – Foods like Pecan Nut are recommended compared to Chestnut. This is because the active ingredients Ellagic Acid and Folic Acid in Chestnut interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Vitamin E and Cianidanol contained in Pecan Nut support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: PECAN NUT IS RECOMMENDED OVER CHESTNUT FOR CHOROID PLEXUS TUMORS ON TREATMENT WITH CHEMOTHERAPY ETOPOSIDE FOR SOME CONDITIONS.

Foods for Genetic Risk of Choroid Plexus Tumors

One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. CIITA and POLQ are two genes whose abnormalities are risk factors for Choroid Plexus Tumors. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Choroid Plexus Tumors can be used as a guide for coming up with a recommended personalized nutrition plan. For Choroid Plexus Tumors gene CIITA has causative impact on biological pathways like Antigen Presentation and Interferon Signaling. And POLQ has a causative impact on biological pathways like DNA Repair, DNA Repair and DNA Repair. Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like CIITA and POLQ should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes CIITA and POLQ should be avoided.

Eat more pulses, Scarlet Bean or Fava Bean?

The active ingredients contained in Scarlet Bean are Vitamin C, Beta-sitosterol, Linolenic Acid, Stigmasterol, Oleic Acid among others. While the active ingredients contained in Fava Bean are Vitamin C, Daidzein, Beta-sitosterol, Ferulic Acid, Linolenic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, MYC Signaling and P53 Signaling. Beta-sitosterol has biological action on biochemical pathways Cell Cycle Checkpoints, Oncogenic Cancer Epigenetics and Apoptosis.

Ferulic Acid can manipulate biochemical pathways DNA Repair. Quercetin has biological action on biochemical pathways DNA Repair. And so on.

For genetic risk of Choroid Plexus Tumors due to abnormalities in genes CIITA and POLQ – Foods like Scarlet Bean are recommended compared to Fava Bean. This is because the active ingredients Ferulic Acid and Quercetin in Fava Bean further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Scarlet Bean together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: SCARLET BEAN IS RECOMMENDED OVER FAVA BEAN FOR REDUCING THE GENETIC RISK OF CHOROID PLEXUS TUMORS DUE TO GENES CIITA AND POLQ

Eat more vegetables, Giant Butterbur or Onion?

The active ingredients contained in Giant Butterbur are Vitamin C, Beta-sitosterol, Vitamin B3, Melatonin, Vitamin A among others. While the active ingredients contained in Onion are Vitamin C, Beta-sitosterol, Diallyl Disulfide, Stigmasterol, Linolenic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, MYC Signaling and P53 Signaling. Beta-sitosterol has biological action on biochemical pathways Cell Cycle Checkpoints, Oncogenic Cancer Epigenetics and Apoptosis.

Quercetin can manipulate biochemical pathways DNA Repair. Diallyl Disulfide has biological action on biochemical pathways DNA Repair. And so on.

For genetic risk of Choroid Plexus Tumors due to abnormalities in genes CIITA and POLQ – Foods like Giant Butterbur are recommended compared to Onion. This is because the active ingredients Quercetin and Diallyl Disulfide in Onion further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Giant Butterbur together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: GIANT BUTTERBUR IS RECOMMENDED OVER ONION FOR REDUCING THE GENETIC RISK OF CHOROID PLEXUS TUMORS DUE TO GENES CIITA AND POLQ

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Eat more fruits, Feijoa or Strawberry?

The active ingredients contained in Feijoa are Lycopene, Vitamin C, Casuarinin, Folic Acid among others. While the active ingredients contained in Strawberry are Ellagic Acid, Vitamin C, Lupeol, Beta-sitosterol, Linolenic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, MYC Signaling and P53 Signaling. Lycopene has biological action on biochemical pathways Cell Cycle Checkpoints, RAS-RAF Signaling and Apoptosis.

Fisetin can manipulate biochemical pathways MYC Signaling. Ellagic Acid has biological action on biochemical pathways MYC Signaling. And so on.

For genetic risk of Choroid Plexus Tumors due to abnormalities in genes CIITA and POLQ – Foods like Feijoa are recommended compared to Strawberry. This is because the active ingredients Fisetin and Ellagic Acid in Strawberry further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Lycopene contained in Feijoa together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: FEIJOA IS RECOMMENDED OVER STRAWBERRY FOR REDUCING THE GENETIC RISK OF CHOROID PLEXUS TUMORS DUE TO GENES CIITA AND POLQ

Eat more nuts, Hazelnut or Macadamia Nut?

The active ingredients contained in Hazelnut are Vitamin E, Linolenic Acid, Oleic Acid, Linoleic Acid, Quercetin among others. While the active ingredients contained in Macadamia Nut are Palmitic Acid, Beta-sitosterol, Lauric Acid, Folic Acid, Myristic Acid and others.

Vitamin E can manipulate biochemical pathways Apoptosis, MYC Signaling and P53 Signaling. Vitamin A has biological action on biochemical pathways Cell Cycle Checkpoints, MYC Signaling and Apoptosis.

Palmitic Acid can manipulate biochemical pathways Oncogenic Cancer Epigenetics and DNA Repair. Lauric Acid has biological action on biochemical pathways MYC Signaling. And so on.

For genetic risk of Choroid Plexus Tumors due to abnormalities in genes CIITA and POLQ – Foods like Hazelnut are recommended compared to Macadamia Nut. This is because the active ingredients Palmitic Acid and Lauric Acid in Macadamia Nut further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin E and Vitamin A contained in Hazelnut together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: HAZELNUT IS RECOMMENDED OVER MACADAMIA NUT FOR REDUCING THE GENETIC RISK OF CHOROID PLEXUS TUMORS DUE TO GENES CIITA AND POLQ


In Summary

An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.

“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.

You can get started NOW and design a personalized nutrition plan for Choroid Plexus Tumors by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

sample-report


References

Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

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