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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which 3 Foods to Avoid for Rosai-Dorfman disease?

Apr 13, 2021

Estimated reading time: 8 minutes
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Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Rosai-Dorfman disease needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Amaranth and Apricot should be eaten when undergoing Prednisone treatment for Rosai-Dorfman disease. On the other hand, for Rosai-Dorfman disease, Allspice and Blackberry should be eaten with treatment of Cladribine. On the same lines, foods like Carob and Catjang Pea should be avoided with treatment of Prednisone for this disorder. If the treatment is Cladribine, then avoid Tallow and Triticale.

Black Seed contains an active ingredient called Thymol. Thymol has CYP (drug metabolizing enzyme) interactions with Prednisone treatment and hence should be avoided. However, Black seed supplements do not have any known CYP interactions with Cladribine treatment for this disorder.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancer/disorders like Rosai-Dorfman disease.



What is Rosai-Dorfman disease?

Rosai-Dorfman disease, previously known as sinus histiocytosis with massive lymphadenopathy, is a rare disorder and a subtype of non-Langerhans cell histiocytosis, characterized by abnormal increase in the production of a specific type of white blood cells called histiocytes in the lymph nodes. The incidence rate of this disorder is only 0.5 per 1 lakh people per year. (Oussama Abla et al, Blood., 2018) This disorder is commonly diagnosed in children and young adults who are about 20 years of age, however, it can occur in people of any age. It is more commonly found in white and black population as compared to Asians.

Rosai-Dorfman disease - symptoms, treatment, diet, foods

Rosai-Dorfman disease has prevalence of certain genetic changes. Some of the genes such as KRAS, MAP2K1, BARD1, and BRAF are known to have genetic abnormalities in this disorder resulting in a change of function. 

The genetic abnormalities found in Rosai-Dorfman disease can influence specific biochemical pathways to drive these disease cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Rosai-Dorfman disease. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Rosai-Dorfman disease genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for this disease nutrition may have to be redesigned.

Why Eating Right Matters for Rosai-Dorfman disease?

In Rosai-Dorfman disease, activation or inhibition of some of the biochemical pathways including RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, MYC Signaling and MAPK Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Rosai-Dorfman disease, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the disease progression.

Example Foods to “Not Eat” and Eat with Prednisone treatment for Rosai-Dorfman disease

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Rosai-Dorfman disease considering only the treatment changes.

Foods to Avoid

Carob : Carob contains active ingredients such as Folic Acid, Quercetin, Phloroglucinol and others. Folic Acid interferes with the impact of Prednisone in Rosai-Dorfman disease by activating a specific biochemical pathway called MYC Signaling. Hence, do not eat Carob with Prednisone treatment for this disease.

Catjang Pea : Catjang Pea contains active ingredients such as Folic Acid, Retinol, Melatonin and others. Folic Acid interferes with the impact of Prednisone in Rosai-Dorfman disease by activating a specific biochemical pathway called MYC Signaling. Hence, do not eat Catjang Pea with Prednisone treatment for this disease.

Foods to Eat

Amaranth :  Amaranth contains active ingredients like Linolenic Acid, Folic Acid, Oleic Acid. Intake of Linolenic Acid along with Prednisone treatment for Rosai-Dorfman disease causes a decrease  in a specific biochemical pathway which is called MAPK Signaling, and this is a very positive effect. Amaranth hence should be eaten with Prednisone treatment for this disease.

Apricot :  Apricot contains active ingredients like Linolenic Acid, Oleic Acid, Quercetin. Intake of Linolenic Acid along with Prednisone treatment for Rosai-Dorfman disease causes a decrease  in a specific biochemical pathway which is called MAPK Signaling, and this is a very positive effect. Apricot hence should be eaten with Prednisone treatment for this disease.

Should I take this Nutritional Supplement for Rosai-Dorfman disease?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymol which have CYP1A2 interactions with Prednisone treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Prednisone treatment efficacy in Rosai-Dorfman disease. Hence, do not take Black Seed supplements with Prednisone treatment for this disease.

Example Foods to “Not Eat” and Eat with Cladribine treatment for Rosai-Dorfman disease

Foods to Avoid

Tallow : Tallow contains active ingredients such as Lauric Acid, Myristic Acid, Palmitic Acid and others. Lauric Acid interferes with the impact of Cladribine in Rosai-Dorfman disease by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid eating foods like Tallow with Cladribine treatment for Rosai-Dorfman disease.

Triticale : Triticale contains active ingredients such as Folic Acid, Lauric Acid, Palmitic Acid and others. Folic Acid interferes with the impact of Cladribine in Rosai-Dorfman disease by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid eating foods like Triticale with Cladribine treatment for Rosai-Dorfman disease.

Foods to Eat

Allspice :  Allspice contains active ingredients like Salicylic Acid, Vitamin C, Eugenol. Intake of Salicylic Acid along with Cladribine treatment for Rosai-Dorfman disease causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Allspice hence should be eaten with Cladribine treatment for this disease.

Blackberry :  Blackberry contains active ingredients like Salicylic Acid, Hyperoside, Quercetin. Intake of Salicylic Acid along with Cladribine treatment for Rosai-Dorfman disease causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Blackberry hence should be eaten with Cladribine treatment for this disease.

Foods to eat and avoid for Rosai-Dorfman Disease

Should I take this Nutritional Supplement for Rosai-Dorfman disease?

Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Cladribine treatment. Black Seed supports the Cladribine treatment for Rosai-Dorfman disease by decreasing the biochemical pathways like MAPK Signaling, MYC Signaling, and PI3K-AKT-MTOR Signaling. Hence Black Seed supplements may be taken with Cladribine treatment for this disease.

Which 3 Foods to Avoid for Rosai-Dorfman disease?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

What are the Symptoms of Rosai-Dorfman disease?

In the initial stages, Rosai-Dorfman disease may not cause any signs or symptoms. However, as the disease progresses, it may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Rosai-Dorfman disease.

  • Enlarged lymph nodes
  • Anemia
  • Breathing difficulties
  • Headaches
  • Seizures
  • Night sweats
  • Bleeding from nose
  • Tonsilitis/Sinusitis
  • Fatigue/Weakness
  • Blood abnormalities
  • Unexplained Weight loss
  • Runny nose or nasal obstruction
  • Nasal deformity

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Rosai-Dorfman disease.

What are the Treatment Options for Rosai-Dorfman disease?

In most of the Rosai-Dorfman disease cases, the symptoms disappear without any treatment. However, in many cases, personalized treatment may be needed to manage specific symptoms. In serious cases, the following treatment options are also used for Rosai-Dorfman disease:

  • Surgery
  • Chemotherapy
  • Radiotherapy
  • Steroid medication

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Rosai-Dorfman disease.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer/disease such as Rosai-Dorfman disease.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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