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What should I Eat?

is the most common question asked by cancer patients.
Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

is the most common question asked by cancer patients. Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

Get your personalized nutrition plan for cancer at 

Get your personalized nutrition plan for cancer at

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Which 3 Foods to Avoid for Phyllodes Tumors?

Apr 13, 2021

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Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Phyllodes Tumors needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Allspice and Blackberry should be eaten when undergoing Pemetrexed Treatment for Phyllodes Tumors. On the same lines, avoid foods like Tallow and Triticale with treatment of Pemetrexed for Phyllodes Tumors.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Phyllodes Tumors.



What is Phyllodes Tumors?

Phyllodes Tumors are a rare form of breast cancer that contains a mixture of cells from connective tissue, and the epithelial layer lining the breast. The incidence rate of this cancer is only 2.1 per 1 lakh people per year. (Shashi Prakash Mishra et al, ISRN Surg., 2013) This cancer is commonly diagnosed in women who are about 45-49 years of age, however, it can occur in women of any age. It is more commonly found in Latina Whites as compared to other ethnic groups.

Phyllodes Tumors - Symptoms, Treatment, Diet, foods

Phyllodes Tumors have prevalence of certain genetic changes. Some of the genes such as TP53, TERT, NF1, and MED12 are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Phyllodes Tumors can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Phyllodes Tumors. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Phyllodes Tumors genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for this cancer may have to be redesigned.

Why Eating Right Matters for Phyllodes Tumors?

In Phyllodes Tumors, activation or inhibition of some of the biochemical pathways including MAPK Signaling, DNA Repair, RAS-RAF Signaling, TGFB Signaling and PI3K-AKT-MTOR Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Phyllodes Tumors, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Pemetrexed treatment for Phyllodes Tumors

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Phyllodes Tumors considering only the treatment changes.

Foods to Avoid

Tallow : Tallow contains active ingredients such as Lauric Acid, Myristic Acid, Palmitic Acid and others. Lauric Acid interferes with the impact of Pemetrexed in Phyllodes Tumors by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Tallow with Pemetrexed treatment for Phyllodes Tumors.

Triticale : Triticale contains active ingredients such as Lauric Acid, Folic Acid, Myristic Acid and others. Lauric Acid interferes with the impact of Pemetrexed in Phyllodes Tumors by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, do not eat Triticale with Pemetrexed treatment for this cancer.

Foods to Eat

Allspice :  Allspice contains active ingredients like Salicylic Acid, Vitamin C, Eugenol. Intake of Salicylic Acid along with Pemetrexed treatment for Phyllodes Tumors causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Allspice hence should be eaten with Pemetrexed treatment for this cancer.

Blackberry :  Blackberry contains active ingredients like Hyperoside, Quercetin, Ellagic Acid. Intake of Hyperoside along with Pemetrexed treatment for Phyllodes Tumors causes a decrease  in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Blackberry hence should be eaten with Pemetrexed treatment for this cancer.

Should I take this Nutritional Supplement for Phyllodes Tumors?

Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Pemetrexed treatment. Black Seed supports the Pemetrexed treatment for Phyllodes Tumors by decreasing the biochemical pathways like MAPK Signaling and PI3K-AKT-MTOR Signaling. Hence Black seed supplements may be taken with Pemetrexed treatment for this cancer.

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What are the Symptoms of Phyllodes Tumors?

In the initial stages, most cancers including Phyllodes Tumors may not cause many signs or symptoms. However, as the disease progresses and the tumor grows, it may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Phyllodes Tumors.

  • Painless lump in the breast
  • The lump may create a visible bulge as it pushes against the skin
  • Ulcer or open wound on the breast skin
  • Skin overlying large tumors may become bluish (due to the dilations of veins)

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Phyllodes Tumors.

What are the Treatment Options for Phyllodes Tumors?

The treatment for Phyllodes Tumors may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for this cancer include:

  • Radiation therapy
  • Chemotherapy
  • Surgery 
    • Removal of the entire breast (Mastectomy)
    • Breast-conserving surgery (partial mastectomy)

Surgery or surgery followed by radiation is the most common treatment regimen for Phyllodes Tumors. Radiotherapy helps to shrink the tumor. The primary role of chemotherapy is in the treatment of metastatic disease. As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Phyllodes Tumors.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Phyllodes Tumors.

“What should I eat?” is the most frequently asked question to cancer dieticians and physicians. The right answer depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan keeps you safe from adverse nutrition interactions.

Get started NOW with answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

Top 10 Foods and Supplements to Avoid for Cancer

Go beyond same nutrition guidelines for everyone and make personalized decisions with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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