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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which 3 Foods to Avoid for Ewing Sarcoma?

Apr 10, 2021

Estimated reading time: 7 minutes
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Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Ewing Sarcoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Aloe Vera and Bamboo should be eaten when undergoing Doxorubicin treatment for Ewing Sarcoma. On the same lines, avoid foods like Margarine and Rhubarb with treatment of Doxorubicin for Ewing Sarcoma. Also, Black Seed contains an active ingredient called Thymoquinone. Thymoquinone has CYP (drug metabolizing enzyme) interactions with Doxorubicin treatment and hence should be avoided.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Ewing Sarcoma.



What is Ewing Sarcoma?

Ewing Sarcoma is a rare cancer that develops from the bones or the soft tissue around the bones. The incidence rate of this cancer is only 0.1 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 10-20 years of age, however, it can occur in people of any age. It is more commonly found in Europeans rather than Africans or Asians.

Ewing Sarcoma- Symptoms, Treatment, diet, foods

Ewing Sarcoma has prevalence of certain genetic changes. Some of the genes such as STAG2, TP53, EZH2, and RYR2 are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Ewing Sarcoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Ewing Sarcoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Ewing Sarcoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Ewing Sarcoma nutrition may have to be redesigned.

Why Eating Right Matters for Ewing Sarcoma?

In Ewing Sarcoma, activation or inhibition of some of the biochemical pathways including Small Molecule Transport, Angiogenesis, MYC Signaling, Wnt Beta-catenin Signaling, P53 Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints, MAPK Signaling, Epithelial To Mesenchymal Transition, Cancer Epigenetics and Apoptosis plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Ewing Sarcoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Doxorubicin treatment for Ewing Sarcoma

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Ewing Sarcoma considering only the treatment changes.

Foods to Avoid

Margarine : Margarine contains active ingredients such as Lauric Acid, Palmitic Acid, Myristic Acid and others. Lauric Acid interferes with the impact of Doxorubicin in Ewing Sarcoma by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid taking foods like Margarine with Doxorubicin treatment for Ewing Sarcoma. (Joo Y Lee et al, J Biol Chem., 2003; Ronald P Mensink et al, m J Clin Nutr., 2003; D M Rocha et al, Atherosclerosis., 2016; Hua Chen et al, Cancer Treat Rev., 2016; Yael Babichev et al, J Transl Med., 2016; Michael J Wagner et al, Oncologist., 2017)

Rhubarb : Rhubarb contains active ingredients such as Linoleic Acid, Rutin, Quercetin and others. Linoleic Acid interferes with the impact of Doxorubicin in Ewing Sarcoma by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, do not eat Rhubarb with Doxorubicin treatment for this cancer. (Bernhard Hennig et al, J Nutr Biochem., 2006; Hua Chen et al, Cancer Treat Rev., 2016; Yael Babichev et al, J Transl Med., 2016; Michael J Wagner et al, Oncologist., 2017)

Foods to Eat

Aloe Vera :  Aloe Vera contains active ingredients like Lupeol, Barbaloin and Acemannan. Intake of Lupeol along with Doxorubicin treatment for Ewing Sarcoma causes a decrease  in a specific biochemical pathway which is called  PI3K-AKT-MTOR Signaling, and this is a very positive effect.  Aloe Vera hence should be eaten with Doxorubicin treatment for Ewing Sarcoma. (Lingli Zhang et al, Eur J Pharmacol., 2015; Hua Chen et al, Cancer Treat Rev., 2016; Yael Babichev et al, J Transl Med., 2016; Michael J Wagner et al, Oncologist., 2017)

Bamboo :  Bamboo contains active ingredients like Vitamin C, Tricin and Linoleic Acid. Intake of Vitamin C along with Doxorubicin treatment for Ewing Sarcoma causes a decrease  in a specific biochemical pathway which is called  PI3K-AKT-MTOR Signaling, and this is a very positive effect.  Bamboo hence should be eaten with Doxorubicin treatment for Ewing Sarcoma. (Mengkai Yang et al, Cytotechnology., 2018; Hua Chen et al, Cancer Treat Rev., 2016; Yael Babichev et al, J Transl Med., 2016; Michael J Wagner et al, Oncologist., 2017)

Foods to eat and avoid for Ewing Sarcoma

Should I take this Nutritional Supplement for Ewing Sarcoma?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 interactions with Doxorubicin treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Doxorubicin treatment efficacy in Ewing Sarcoma. Hence, avoid taking Black seed supplements along with Doxorubicin for this cancer. (Ahmed A Albassam et al, Saudi Pharm J., 2018; Pius S Fasinu et al, Front Oncol., 2019)

Which 3 Foods to Avoid for Ewing Sarcoma?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

What are the Symptoms of Ewing Sarcoma?

In the initial stages, most cancers including Ewing Sarcoma may not cause any signs or symptoms. However, as the disease progresses, Ewing Sarcoma may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Ewing Sarcoma.

  • Bone pain 
  • Tender Lump or swelling near the skin
  • Bone fractures without injury
  • Unexplained weight loss
  • Fatigue/weakness
  • High fever

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Ewing Sarcoma.

What are the Treatment Options for this Cancer?

The treatment for Ewing Sarcoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for this Cancer include:

  • Surgery
  • Radiation therapy
  • Chemotherapy
  • Combination of Chemotherapy, Surgery and Radiotherapy

Surgery or surgery followed by radiation is the most common treatment regimen for Ewing Sarcoma. Radiotherapy helps to shrink the tumor. The primary role of chemotherapy is in the treatment of metastatic disease. As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Ewing Sarcoma.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Ewing Sarcoma.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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