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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which 3 Foods to Avoid for Aggressive NK Cell Leukemia?

Apr 7, 2021

Estimated reading time: 9 minutes
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Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Aggressive NK Cell Leukemia needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Cabbage and Celery should be eaten when undergoing Ifosfamide treatment for Aggressive Natural Killer Cell Leukemia. On the other hand, for Aggressive NK Cell Leukemia, Almond and Beetroot should be eaten with treatment of Etoposide. On the same lines, foods like Brussels Sprout and Cauliflower should be avoided with treatment of Ifosfamide for Aggressive NK Cell Leukemia. If the treatment is Etoposide, then avoid Amaranth and Bell Pepper.

Black Seed supplements contain an active ingredient called Thymoquinone which has CYP (drug metabolizing enzyme) interactions with Etoposide treatment and hence should be avoided.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Aggressive NK Cell Leukemia.



What is Aggressive Natural Killer Cell Leukemia?

Aggressive NK Cell Leukemia is a rare cancer characterized by an aggressive, systemic proliferation of natural killer cells (NK cells). This cancer is commonly diagnosed in people who are about 20-50 years of age, however, it can occur in people of any age. It is more commonly found in Asians as compared to other ethnicities.

Aggressive Natural Killer (NK) Cell Leukemia - Symptoms, Treatment, Diet, Foods

Aggressive NK Cell Leukemia has prevalence of certain genetic changes. Some of the genes such as DDX3X, STAT3, PTPN4, and BCOR are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Aggressive NK Cell Leukemia can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Aggressive Natural Killer Cell Leukemia. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Aggressive NK Cell Leukemia genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Aggressive NK Cell Leukemia nutrition may have to be redesigned.

Why Eating Right Matters for Aggressive NK Cell Leukemia?

In Aggressive Natural Killer Cell Leukemia, activation or inhibition of some of the biochemical pathways including MAPK Signaling, P53 Signaling, MYC Signaling, Interferon Signaling, PI3K-AKT-MTOR Signaling and JAK-STAT Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Aggressive NK Cell Leukemia, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Ifosfamide treatment for Aggressive Natural Killer Cell Leukemia

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Aggressive Natural Killer Cell Leukemia considering only the treatment changes.

Foods to Avoid

Brussels Sprout : Brussels Sprout contains active ingredients such as Folic Acid, Sinapic Acid, Oleic Acid and others. Folic Acid interferes with the impact of Ifosfamide in Aggressive Natural Killer Cell Leukemia by blocking a specific biochemical pathway called P53 Signaling. Hence, do not eat Brussels Sprout with Ifosfamide treatment for Aggressive NK Cell Leukemia. (Petar Novakovic et al, Carcinogenesis, 2006; Siba El Hussein et al, Cancers (Basel)., 2020)

Cauliflower : Cauliflower contains active ingredients such as Folic Acid, Oleic Acid, Linolenic Acid and others. As mentioned above, Folic Acid interferes with the impact of Ifosfamide in Aggressive Natural Killer Cell Leukemia by blocking a specific biochemical pathway called P53 Signaling. Hence, do not eat Cauliflower with Ifosfamide treatment for Aggressive NK Cell Leukemia. (Petar Novakovic et al, Carcinogenesis, 2006; Siba El Hussein et al, Cancers (Basel)., 2020)

Foods to Eat

Cabbage :  Cabbage contains active ingredients like Brassinin, Isorhamnetin and Vitamin C. Intake of Brassinin along with Ifosfamide treatment for Aggressive Natural Killer Cell Leukemia causes a decrease  in a specific biochemical pathway which is called JAK-STAT Signaling, and this is a very positive effect. Cabbage hence should be eaten with Ifosfamide treatment for Aggressive NK Cell Leukemia. (Jong Hyun Lee et al, Oncotarget., 2015; Mustafa Aziz Hatiboglu et al, Int J Cancer., 2012; Siba El Hussein et al, Cancers (Basel)., 2020)

Celery :  Celery contains active ingredients like Angelicin and Alpha-terpinyl Acetate. Intake of Angelicin along with Ifosfamide treatment for Aggressive Natural Killer Cell Leukemia causes a decrease in a specific biochemical pathway which is called JAK-STAT Signaling, and this is a very positive effect. Celery hence should be eaten with Ifosfamide treatment for Aggressive NK Cell Leukemia. (Fang Liu et al, J Surg Res., 2013; Ju-Hwa Kim et al, Biochem Pharmacol., 2010; Mustafa Aziz Hatiboglu et al, Int J Cancer., 2012; Siba El Hussein et al, Cancers (Basel)., 2020)

Should I take this Nutritional Supplement for Aggressive Natural Killer Cell Leukemia?

Black Seed : Black Seed nutritional supplements have no interactions with Ifosfamide treatment. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Ifosfamide treatment efficacy in Aggressive Natural Killer Cell Leukemia. Hence, do not take Black Seed supplements with Ifosfamide treatment for this cancer.

Example Foods to “Not Eat” and Eat with Etoposide treatment for Aggressive NK Cell Leukemia

Foods to Avoid

Amaranth : Amaranth contains active ingredients such as Folic Acid, Oleic Acid, Linolenic Acid and others. Folic Acid interferes with the impact of Etoposide in Aggressive Natural Killer Cell Leukemia by activating a specific biochemical pathway called MYC Signaling. Hence, do not eat Amaranth with Etoposide treatment for Aggressive NK Cell Leukemia. (B D Cowley Jr et al, J Biol Chem., 1989; Bidwell GL 3rd and Raucher D, Biochemical Pharmacology., 2006; Motoko Yamaguchi et al, Cancer Sci., 2008)

Bell Pepper : Bell Pepper contains active ingredients such as Capsaicin, Folic Acid, Isorhamnetin and others. Capsaicin interferes with the impact of Etoposide in Aggressive Natural Killer Cell Leukemia by activating a specific biochemical pathway called MYC Signaling. Hence, do not eat Bell Pepper with Etoposide treatment for Aggressive NK Cell Leukemia. (J D Kim et al, Cancer Lett., 1997; Bidwell GL 3rd and Raucher D, Biochemical Pharmacology., 2006; Motoko Yamaguchi et al, Cancer Sci., 2008)

Foods to Eat

Almond and Beetroot :  Almond and Beetroot contain active ingredients like Vitamin E, Oleic Acid, and others. Intake of Vitamin E along with Etoposide treatment for Aggressive Natural Killer Cell Leukemia causes a decrease in a specific biochemical pathway which is called MAPK Signaling, and this is a very positive effect. Almond and Beetroot hence should be eaten with Etoposide treatment for Aggressive NK Cell Leukemia. (B Ekstrand-Hammarström et al, Clin Exp Immunol., 2007; B Marengo et al, Cell Death Dis., 2013; Motoko Yamaguchi et al, Cancer Sci., 2008)

Foods to eat and avoid for Aggressive Natural Killer Cell Leukemia

Should I take this Nutritional Supplement for Aggressive NK Cell Leukemia?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 and CYP1A2 interactions with Etoposide treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Etoposide treatment efficacy in Aggressive NK Cell Leukemia. Hence, do not take Black Seed supplements with Etoposide treatment for this cancer. (Ahmed A Albassam et al, Saudi Pharm J.,2018; Xiaoliang Zhuo et al, Drug Metab Dispos., 2004; T Kawashiro et al, J Pharmacol Exp Ther., 1998)

Which 3 Foods to Avoid for Aggressive NK Cell Leukemia?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

What are the Symptoms of Aggressive NK Cell Leukemia?

In the initial stages, most cancers including Aggressive NK Cell Leukemia may not cause any signs or symptoms. However, as the disease progresses, Aggressive NK Cell Leukemia may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Aggressive NK Cell Leukemia.

  • unexplained fever
  • night sweats
  • unexplained weight loss
  • enlarged liver or spleen
  • abnormally low number of healthy blood cells
  • enlarged lymph nodes

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Aggressive Natural Killer Cell Leukemia.

What are the Treatment Options for Aggressive NK Cell Leukemia?

The treatment for Aggressive Natural Killer Cell Leukemia may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history. The treatment options for Aggressive NK Cell Leukemia include:

  • Chemotherapy
  • Stem cell Transplantation
  • Medications like steroids for specific symptoms

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Aggressive Natural Killer Cell Leukemia.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Aggressive Natural Killer Cell Leukemia.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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