No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Hemangioblastoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Alfalfa and Allspice should be eaten when undergoing Bevacizumab treatment for Hemangioblastoma. On the same lines, foods like Buttermilk and Chicory should be avoided with treatment of Bevacizumab for Hemangioblastoma. Also, Vitamin B2 supplements do not show benefit on biochemical pathways that could improve the Bevacizumab treatment efficacy in Hemangioblastoma and should be avoided.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Hemangioblastoma.
What is Hemangioblastoma?
Hemangioblastoma is a rare type of tumor that can occur in the brain, spinal cord, and retina. It is usually non-cancerous or benign. The incidence rate of this cancer is only 0.141 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 20 to 50 years of age, however, it can occur in people of any age. It is more commonly found in men as compared to women.
Hemangioblastoma has prevalence of certain genetic changes. Some of the genes such as VHL, FANCA, NF1, and TET2 are known to have genetic abnormalities in this tumor resulting in a change of function.
The genetic abnormalities found in Hemangioblastoma can influence specific biochemical pathways to drive these tumor cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Hemangioblastoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Hemangioblastoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or tumor diagnosis – it may impact the nutrition and the nutrition/diet plan for Hemangioblastoma nutrition may have to be redesigned.
Why Eating Right Matters for Hemangioblastoma?
In Hemangioblastoma, activation or inhibition of some of the biochemical pathways including Angiogenesis, Dna Repair, TGFB Signaling, PI3K-AKT-MTOR Signaling, Hypoxia and MAPK Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Hemangioblastoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Bevacizumab treatment for Hemangioblastoma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Hemangioblastoma considering only a specific treatment- Bevacizumab.
Foods to Avoid with Bevacizumab treatment
Buttermilk : Buttermilk contains active ingredients such as Lauric Acid, Vitamin D3, Retinol and others. Lauric Acid interferes with the impact of Bevacizumab in Hemangioblastoma by activating a specific biochemical pathway called MAPK Signaling. Hence, do not take Buttermilk with Bevacizumab treatment for Hemangioblastoma. (Rosamaria Lappano et al, Cell Death Discov., 2017; Chelsea C Estrada et al, J Am Soc Nephrol., 2019; Gloria Mak et al, Neurooncol. Adv. 2020)
Chicory : Chicory contains active ingredients such as Apigenin, Folic Acid, Delphinidin and others. Apigenin interferes with the impact of Bevacizumab in Hemangioblastoma by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, do not eat Chicory with Bevacizumab treatment for Hemangioblastoma. (John D Hainsworth et al, J Neurooncol., 2019; Sung Min Ju et al, Evid Based Complement Alternat Med., 2015; Gloria Mak et al, Neurooncol. Adv., 2020)
Foods to Eat with Bevacizumab treatment
Alfalfa : Alfalfa contains active ingredients like Vitamin C, 7-4′-dihydroxyflavone and Linolenic Acid. Intake of Vitamin C along with Bevacizumab treatment for Hemangioblastoma causes a decrease in a specific biological process called Angiogenesis, and this is a very positive effect. Alfalfa hence should be eaten with Bevacizumab treatment for Hemangioblastoma. (Nina A Mikirova et al, J Transl Med., 2008; Ayman I Omar, J Med Case Rep., 2012)
Allspice : Allspice contains active ingredients like Vitamin C, Eucalyptol and Salicylic Acid. As mentioned above, the intake of Vitamin C along with Bevacizumab treatment for Hemangioblastoma causes a decrease in a specific biological process which is called Angiogenesis, and this is a very positive effect. Allspice hence should be eaten with Bevacizumab treatment for Hemangioblastoma. (Nina A Mikirova et al, J Transl Med., 2008; Ayman I Omar, J Med Case Rep., 2012)
Should I take this Nutritional Supplement with Bevacizumab treatment?
Vitamin B2 : Vitamin B2 nutritional supplements have no interactions with Bevacizumab treatment. However, Vitamin B2 supplement does not show benefit on other biochemical pathways that could improve the Bevacizumab treatment efficacy in Hemangioblastoma. Hence, it is better to avoid taking Vitamin B2 nutritional supplements during Bevacizumab treatment for Hemangioblastoma.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of Hemangioblastoma?
In the initial stages, most tumors including Hemangioblastoma may not cause any signs or symptoms. However, as the disease progresses, Hemangioblastoma may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Hemangioblastoma depending on the location of the tumor.
- loss of balance
- loss of coordination
- muscle weakness/numbness
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Hemangioblastoma.
What are the Treatment Options for Hemangioblastoma?
The treatment for Hemangioblastoma may be decided based on different factors including the location of the tumor, disease characteristics, symptoms, patient’s general health and medical history, whether the tumor can be removed completely by surgery and whether the disease was just diagnosed or had come back. The treatment options for Hemangioblastoma include:
- Targeted Therapy
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Hemangioblastoma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancers/tumors such as Hemangioblastoma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.