No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Hemangiopericytoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Squash and Beetroot should be eaten when undergoing Cisplatin treatment for Hemangiopericytoma. On the other hand, for Hemangiopericytoma, Walnut and Common Pea should be eaten with treatment of Docetaxel. On the same lines, foods like Amaranth and Cauliflower should be avoided with treatment of Cisplatin for Hemangiopericytoma. If the treatment is Docetaxel, then avoid Tallow and Coriander.
Vitamin B3 supplement has CYP (drug metabolizing enzyme) interactions with Cisplatin and Docetaxel treatments and hence this supplement should be avoided when taking Cisplatin or Docetaxel treatment for Hemangiopericytoma.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Hemangiopericytoma.
What is Hemangiopericytoma?
Hemangiopericytoma is a rare type of soft-tissue sarcoma that develops in the pericytes, the cells arranged in the walls of the capillaries. The incidence rate of this cancer is only 0.060 per 1 lakh people per year (Kewei Wang et al, Biomed Res Int., 2020). This cancer is commonly diagnosed in people who are about 38–42 years years of age, however, it can occur in people of any age. It is more commonly found in men as compared to women.
Hemangiopericytoma has prevalence of certain genetic changes. Some of the genes such as TERT, TP53, COL7A1, and ENG are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Hemangiopericytoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Hemangiopericytoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Hemangiopericytoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Hemangiopericytoma nutrition may have to be redesigned.
Why Eating Right Matters for Hemangiopericytoma?
In Hemangiopericytoma, activation or inhibition of some of the biochemical pathways including Oxidative Stress, PI3K-AKT-MTOR Signaling and Cell Cycle Checkpoints plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Hemangiopericytoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Cisplatin treatment for Hemangiopericytoma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show examples of nutrition/diet for Hemangiopericytoma considering one specific treatment.
Foods to Avoid with Cisplatin treatment
Amaranth : Amaranth contains active ingredients such as Citric Acid, Lutein and others. Citric Acid interferes with the impact of Cisplatin in Hemangiopericytoma by activating a specific biochemical pathway called ROS-NRF2 which protects cancer cells from a biological process called oxidative stress. Oxidative stress has been shown to induce apoptosis or cell death in different cancer cells. Hence, do not eat Amaranth with Cisplatin treatment for Hemangiopericytoma. (Soraya Sajadimajd et al, Curr Cancer Drug Targets., 2018; Omar M E Abdel-Salam et al, J Med Food., 2014; Wangie Yu et al, Scientific Reports, 2018; Marc C Chamberlain et al, Neurosurgery., 2008)
Cauliflower : Cauliflower contains active ingredients such as Citric Acid, Indole-3-carbinol and others. As mentioned above, ingredients like Citric Acid interfere with the impact of Cisplatin in Hemangiopericytoma by activating a specific biochemical pathway called ROS-NRF2 which protects cancer cells from a biological process called oxidative stress. Hence, do not eat Cauliflower with Cisplatin treatment for Hemangiopericytoma. (Soraya Sajadimajd et al, Curr Cancer Drug Targets., 2018; Omar M E Abdel-Salam et al, J Med Food., 2014; Wangie Yu et al, Scientific Reports, 2018; Marc C Chamberlain et al, Neurosurgery., 2008)
Foods to Eat with Cisplatin treatment
Squash and Beetroot : Foods such as Squash and Beetroot contain active ingredients like Vitamin E, Beta-sitosterol and Linolenic Acid. Intake of Vitamin E along with Cisplatin treatment for Hemangiopericytoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Squash and Beetroot hence should be eaten with Cisplatin treatment for Hemangiopericytoma. (Paul W Sylvester et al, Anticancer Agents Med Chem., 2013; Y Zhang et al, Neoplasma., 2016; Yuichi Yamada et al, Cancer., 2013)
Should I take this Nutritional Supplement with Cisplatin treatment?
Vitamin B3 : Vitamin B3 nutritional supplements have CYP3A4 interactions with Cisplatin treatment, and hence should not be used. Also, Vitamin B3 supplement interferes with the impact of Cisplatin in Hemangiopericytoma by improving the capacity of a biological process called DNA Repair. Hence, it is better to avoid taking Vitamin B3 supplements to stay safe while on Cisplatin treatment for Hemangiopericytoma. (Cédric Gaudineau et al, Biochem Biophys Res Commun., 2004; Pius S Fasinu et al, Front Onco., 2019; Devita Surjana et al, J Nucleic Acids., 2010)
Example Foods to “Not Eat” and Eat with Docetaxel treatment for Hemangiopericytoma
Foods to Avoid with Docetaxel treatment
Tallow : Tallow contains active ingredients such as Myristic Acid, Palmitic Acid, Lauric Acid and others. Myristic Acid interferes with the effect of Docetaxel in Hemangiopericytoma by activating cell cycle and inhibiting apoptosis . Hence, do not eat Tallow with Docetaxel treatment for Hemangiopericytoma. (ReLi Zeng et al, PLoS One., 2008; Jacques-Olivier Bay et al, Int J Cancer., 2006; Yunjung Choi et al, Cancer Res Treat., 2018 )
Coriander : Coriander contains active ingredients such as Rutin, D-limonene, Psoralen and others. Rutin interferes with the impact of Docetaxel in Hemangiopericytoma by activating a specific biological process called Microtubule dynamics. Hence, do not eat Coriander with Docetaxel treatment for Hemangiopericytoma. (Sabina Tabaczar et al, Postepy Hig Med Dosw (Online)., 2010; Yunjung Choi et al, Cancer Res Treat., 2018)
Foods to Eat with Docetaxel treatment
Walnut : Walnut contains active ingredients like Beta-sitosterol, Carvacrol and Chlorogenic acid. Intake of Beta-sitosterol along with Docetaxel treatment for Hemangiopericytoma interferes with a biological process called microtubule assembly dynamics, and this is a very positive effect. Walnut hence should be eaten with Docetaxel treatment for Hemangiopericytoma. (Tejashree Mahaddalkar et al,Eur J Pharmacol., 2015; Sabina Tabaczar et al, Postepy Hig Med Dosw (Online)., 2010; Yunjung Choi et al, Cancer Res Treat., 2018)
Common Pea: Common Pea contains active ingredients like Beta-sitosterol, Daidzein and Lupeol. As mentioned before, the intake of Beta-sitosterol along with Docetaxel treatment for Hemangiopericytoma interferes with a biological process called microtubule assembly dynamics, and this is a very positive effect. Common Pea hence should be eaten with Docetaxel treatment for Hemangiopericytoma. (Tejashree Mahaddalkar et al,Eur J Pharmacol., 2015; Sabina Tabaczar et al, Postepy Hig Med Dosw (Online)., 2010; Yunjung Choi et al, Cancer Res Treat., 2018)
Should I take this Nutritional Supplement with Docetaxel treatment?
Vitamin B3 : Vitamin B3 nutritional supplements have CYP3A4 interactions with Docetaxel treatment, and hence should not be used. Also, Vitamin B3 supplement does not show benefit on other biochemical pathways that could improve the Docetaxel treatment efficacy in Hemangiopericytoma. Hence, it is better to avoid taking Vitamin B3 supplements to stay safe while on Docetaxel treatment for Hemangiopericytoma.(Cédric Gaudineau et al, Biochem Biophys Res Commun., 2004; Pius S Fasinu et al, Front Onco., 2019)
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of Hemangiopericytoma?
In the initial stages, most cancers including Hemangiopericytoma may not cause any signs or symptoms. However, as the disease progresses, Hemangiopericytoma may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Hemangiopericytoma.
- headache, nausea and vomiting
- lump or a painless swelling
- pain or soreness when the tumor presses on nearby nerves or muscles
- limping or poor coordination of the limbs
- low blood sugar
- gait disturbances
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Hemangiopericytoma.
What are the Treatment Options for Hemangiopericytoma?
The treatment for Hemangiopericytoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back.
The treatment options for Hemangiopericytoma include:
- Radiation therapy
Surgery and radiosurgery are the most common treatment regimens for Hemangiopericytoma. As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Hemangiopericytoma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Hemangiopericytoma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.