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What should I Eat?

is the most common question asked by cancer patients.
Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

is the most common question asked by cancer patients. Choose food and nutritional supplements which reduces adverse interactions with your cancer treatment and support them.

Get your personalized nutrition plan for cancer at 

Get your personalized nutrition plan for cancer at

Which 3 Foods to Avoid for Ependymoma?

Mar 6, 2021

Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Ependymoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Lettuce and Potato should be eaten when undergoing Temozolomide treatment for Ependymoma. On the other hand, for Ependymoma, Blackberry and Okra should be eaten with treatment of Radiation. On the same lines, foods like Margarine and Oil Palm should be avoided with treatment of Temozolomide for Ependymoma.  If the treatment is Radiation,  then avoid Spearmint.

Curcumin has no reported interactions with Temozolomide and Radiation treatments and can help improve the efficacy of these treatments in Ependymoma. 

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Ependymoma.



What is Ependymoma?

Ependymoma is a rare cancer that develops in the ependymal cells in the brain and spinal cord. The incidence rate of this cancer is only 0.2 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 44 years of age, however, it can occur in people of any age. It is commonly found in white and non-hispanic people as compared to African Americans.

Symptoms, Treatment and Diet for Ependymoma

Ependymoma has prevalence of certain genetic changes. Some of the genes such as FANCE, RHBDF2, DOCK8, and EME1 are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Ependymoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Ependymoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Ependymoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Ependymoma nutrition may have to be redesigned. 

Why Eating Right Matters for Ependymoma?

In Ependymoma, activation or inhibition of some of the biochemical pathways including PI3K-AKT-MTOR Signaling, ERK Signaling, MAPK Signaling, Epithelial to Mesenchymal Transition, Microtubule Dynamics, DNA Repair and Cancer Epigenetics plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Ependymoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Temozolomide treatment for Ependymoma

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show changes in nutrition/diet for Ependymoma considering only the treatment changes.

Foods to Avoid

Margarine and Oil Palm: Margarine and Oil (Palm) contain active ingredients such as Lauric Acid, Palmitic Acid, and others. Lauric Acid interferes with the impact of Temozolomide in Ependymoma by activating specific biochemical pathways called ERK, MAPK and PI3K signaling. Hence, do not eat Margarine and Oil (Palm) with Temozolomide treatment for Ependymoma. (Qiang Li et, Ann Transl Med., 2020; Joo Y Lee et al, J Biol Chem., 2003)

Foods to Take 

Lettuce and Potato : Lettuce and Potato contains active ingredients like Chlorogenic Acid, Oleic Acid, and others. Intake of Chlorogenic Acid along with Temozolomide treatment for Ependymoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR, and this is a very positive effect. Lettuce and Potato hence should be eaten with Temozolomide treatment for Ependymoma. (Hazel A Rogers et al, Clin Cancer Res. 2013, Xiaokang Wang et al, J Pharm Pharmacol., 2019)

Should I take this Nutritional Supplement for Ependymoma?

Curcumin : Curcumin has no known reported CYP (drug metabolizing enzyme) interactions with Temozolomide treatment. Curcumin supports the Temozolomide treatment for Ependymoma by decreasing the biochemical pathways/processes called Angiogenesis, DNA Repair, MAPK Signaling, Hypoxia and PI3K-AKT-MTOR Signaling, and increasing pathways like RUNX Signaling. Hence, Curcumin may be taken along with Temozolomide for Ependymoma. (Cheppail Ramachandran et al, J Complement Integr Med., 2012; Haitao Yin et al, Oncol Rep., 2014)

Example Foods to “Not Eat” and Eat with Radiation treatment for Ependymoma

Foods to Avoid

Spearmint : Spearmint contains active ingredients such as Isothymonin, Retinol, D-limonene and others. Isothymonin interferes with the impact of Radiation in Ependymoma by enhancing specific biological processes called Mesenchymal Transition and Microtubule Dynamics. Hence, do not eat Spearmint with Radiation treatment for Ependymoma. (Poonam Yadav, et al,  Biomed Pharmacother., 2019; Yuan Wu et al, J Mol Cell Biol., 2020; Shinsuke Hashida et al, Oncol Rep., 2015)

Foods to Eat

Blackberry and Okra : Blackberry and Okra contain active ingredients like Salicylic Acid and others. Intake of Salicylic Acid along with Radiation treatment for Ependymoma causes a decrease in a specific biochemical process which is called  DNA Repair, and this is a very positive effect. Blackberry and Okra hence should be eaten with Radiation treatment for Ependymoma. (Rakesh Dachineni et al, Mol Cancer Res., 2016; Carsten Müller-Tidow et al, Mol Cell Biol., 2004; Forrest M Kievit et al, Mol Oncol., 2015)

Should I take this Nutritional Supplement for Ependymoma?

Curcumin : Curcumin nutritional supplements have no known reported CYP (drug metabolizing enzyme) interactions with Radiation treatment. Also, Curcumin supplement  supports the Radiation treatment for Ependymoma by decreasing the biochemical pathways and processes like Epithelial to Mesenchymal Transition, MAPK Signaling, Focal Adhesion, JAK-STAT Signaling, Microtubule Dynamics, PI3K-AKT-MTOR Signaling, Cell Cycle and RAS-RAF Signaling. Hence, Curcumin may be taken along with Radiation for Ependymoma. (Marcela Gallardo et al, Int J Oncol., 2016; Qing Wang et al, Am J Cancer Res., 2017; Krishnan M Dhandapani et al, J Neurochem., 2007)

Is Curcumin good for Breast Cancer? | Get Personalized Nutrition For Breast Cancer

Top 10 Foods and Supplements to Avoid for Cancer

Go beyond same nutrition guidelines for everyone and make personalized decisions with confidence.

What are the Symptoms of Ependymoma?

In the initial stages, most cancers including Ependymoma may not cause any signs or symptoms as they grow very slowly over years. However, as the disease progresses, it may start showing symptoms. The signs and symptoms of Ependymoma may vary greatly depending on the size, location and growth rate of the tumor.

Following are some of the signs and symptoms that may be caused by Ependymoma.

  • Severe, frequent headaches
  • Nausea and vomiting
  • Eye problems including blurred or double vision
  • Numbness or loss of movement in an arm or a leg
  • Difficulty with balance/walking
  • Seizures
  • Hearing problems
  • Speech problems
  • Feeling confused or irritated
  • Personality/behavior changes
  • Stiffness or pain in the neck

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Ependymoma.

What are the Treatment Options for Ependymoma?

The treatment for Ependymoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Ependymoma include:

  • Close monitoring
  • Surgery
  • Radiation
  • Chemotherapy
  • Targeted therapy

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Ependymoma.

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Ependymoma.

“What should I eat?” is the most frequently asked question to cancer dieticians and physicians. The right answer depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan keeps you safe from adverse nutrition interactions.

Get started NOW with answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

Top 10 Foods and Supplements to Avoid for Cancer

Go beyond same nutrition guidelines for everyone and make personalized decisions with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.